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在新生小鼠静脉注射
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JoVE Journal Biology
Intravenous Injections in Neonatal Mice
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在新生小鼠静脉注射

DOI:
10.3791/52037-v

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05:17 min

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November 11, 2014

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, ,
1Department of Neuroscience,Ohio State University, 2Center for Gene Therapy, Nationwide Children’s Hospital Research Institute,Ohio State University

Chapters

  • 00:05Title
  • 00:52Preparation and Injection Procedure
  • 03:06Post-Injection
  • 04:04Results: GFP Expression after Neonate Intravenous Injection
  • 04:55Conclusion

Summary

Automatic Translation

Automatic Translation

儿科疾病的动物模型可以体验早期发病和严重的疾病进展。临床相关治疗交付给年轻小鼠模型可以在技术上难度。这个协议描述了一种非侵入性的静脉内注射的方法在生命的最初2日龄新生小鼠。

Tags

Intravenous InjectionNeonatal MiceTemporal VeinAdeno-associated VirusAAVTransgene ExpressionTherapeutic DeliveryMouse ModelsEarly Onset Disease

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