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JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Modeling Mucosal Candidiasis in Larval Zebrafish by Swimbladder Injection
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Journal (Immunology and Infection)
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Modeling Mucosal Candidiasis in Larval Zebrafish by Swimbladder Injection

Article DOI: 10.3791/52182
November 27th, 2014 •
1, 1, 1,2
1Department of Molecular and Biomedical Sciences, University of Maine, 2Graduate School of Biomedical Sciences and Engineering, University of Maine

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November 27th, 2014

In vivo spatio-temporal interactions of pathogen and immune defenses at the mucosal level are not easily imaged in existing vertebrate hosts. The method presented here describes a versatile platform to study mucosal candidiasis in live vertebrates using the swimbladder of the juvenile zebrafish as an infection site.

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