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JoVE Journal
Immunology and Infection

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Modeling Mucosal Candidiasis in Larval Zebrafish by Swimbladder Injection
 

Modeling Mucosal Candidiasis in Larval Zebrafish by Swimbladder Injection

Article DOI: 10.3791/52182 06:28 min
November 27th, 2014

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Summary November 27th, 2014

In vivo spatio-temporal interactions of pathogen and immune defenses at the mucosal level are not easily imaged in existing vertebrate hosts. The method presented here describes a versatile platform to study mucosal candidiasis in live vertebrates using the swimbladder of the juvenile zebrafish as an infection site.

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