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Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice
 

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

Article doi: 10.3791/52206
December 2nd, 2014 Usage Statistics

Summary December 2nd, 2014

Heart failure is the leading cause of hospitalization and a major cause of mortality. A model of permanent ligation of the left anterior descending coronary artery in mice is applied to investigate ventricular remodelling and cardiac dysfunction post-myocardial infarction. The technique of invasive hemodynamic measurements in mice is presented.

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