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A Method of Nodose Ganglia Injection in Sprague-Dawley Rat

Article DOI: 10.3791/52233 • 09:28 min • November 25th, 2014
November 25th, 2014 •
1,3, 1,2, 1,3
1Center for Narcolepsy, Sleep and Health Research, University of Illinois at Chicago, 2Department of Pharmacology, University of Illinois at Chicago, 3Department of Biobehavioral Health Science, University of Illinois at Chicago

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Summary
Automatic Translation

Afferent vagal signaling transmits important information to central nervous system from receptors located in organs of the abdomen and thorax. The nodose ganglia of vagus nerves contain many types of receptors that modulate vagal activity. This protocol describes a method of local injections of neurochemicals into the nodose ganglia.

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Nodose Ganglia Injection Sprague-Dawley Rat Afferent Signaling Vagus Nerve Central Nervous System Receptors Abdominal Organs Thoracic Organs Stimuli Heart Rate Blood Pressure Bronchopulmonary Irritation Gastrointestinal Distension Nucleus Of Solitary Tract Medulla Cell Bodies Neurochemicals Vagal Afferents Peripheral Drug Treatments Sleep Apnea Gastroesophageal Reflux Disease Chronic Cough Injection Protocol Neurochemical Study Afferent Nerve Activity
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