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Method of Isolated Ex Vivo Lung Perfusion in a Rat Model: Lessons Learned from Developing a Rat EVLP Program
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal Medicine
Method of Isolated Ex Vivo Lung Perfusion in a Rat Model: Lessons Learned from Developing a Rat EVLP Program
DOI:

08:59 min

February 25, 2015

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Chapters

  • 00:05Title
  • 01:45Ex Vivo Lung Perfusion (EVLP) Setup
  • 02:41Extraction and Initial Ventilation of the Rat Lungs
  • 06:11Ex Vivo Perfusion of the Lungs
  • 07:51Results: Ex Vivo Lung Perfusion in Rats
  • 08:33Conclusion

Summary

Automatic Translation

Ex-Vivo Lung Perfusion (EVLP) has allowed lung transplantation in humans to become more readily available by enabling the ability to assess organs and expand the donor pool. Here, we describe the development of a rat EVLP program and refinements that allow for a reproducible model for future expansion.

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