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JoVE Journal
Bioengineering

This content is Open Access.

Sample Preparation Strategies for Mass Spectrometry Imaging of 3D Cell Culture Models
 

Sample Preparation Strategies for Mass Spectrometry Imaging of 3D Cell Culture Models

Article DOI: 10.3791/52313
December 5th, 2014

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Summary December 5th, 2014

Immortalized cancer cell lines can be grown as 3D cell cultures, a valuable model for biological research. This protocol describes mass spectrometry imaging of 3D cell cultures, including improvements in the sample preparation platform. The goal of this protocol is to instruct users to prepare 3D cell cultures for mass spectrometry imaging analysis.

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