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JoVE Journal
Developmental Biology

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人类多能干细胞的模板微图案用于探测分化命运的空间组织
 
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人类多能干细胞的模板微图案用于探测分化命运的空间组织

Article DOI: 10.3791/54097-v 08:07 min June 17th, 2016
June 17th, 2016

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Summary

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人多能干细胞(hPSCs)具有分化和自我组织成不同的组织型态的内在能力;尽管这需要空间环境梯度的表现。我们提出模版图案化作为一种​​简单而可靠的方法,以产生生物化学和机械梯度用于控制HPSC分化模式。

Tags

发育生物学,第112,人类多能干细胞,细胞图案化,模板,分化命运,空间组织,组织图案,胚胎发育
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