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JoVE Journal
Immunology and Infection

This content is Open Access.

Generation of Immature, Mature and Tolerogenic Dendritic Cells with Differing Metabolic Phenotypes
 

Generation of Immature, Mature and Tolerogenic Dendritic Cells with Differing Metabolic Phenotypes

Article doi: 10.3791/54128
June 22nd, 2016 Usage Statistics

Summary June 22nd, 2016

Immature dendritic cells can be selectively differentiated into tolerogenic or mature dendritic cells to regulate the balance between immunity and tolerance. This work presents a means to generate from immature monocyte derived dendritic cells (moDCs), in vitro tolerogenic and mature moDCs that differ in metabolic phenotypes.

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