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一个两亲性共聚物的阴离子聚合通过π-π堆积作用稳定嵌段共聚物胶束的制备
JoVE Journal
Chemistry
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JoVE Journal Chemistry
Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
DOI:

10:53 min

October 10, 2016

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Chapters

  • 00:05Title
  • 00:56Description of the Key Steps of Living Anionic Polymerization: Distillation and Transfer
  • 06:11Procedure for Loading Doxorubicin into BCMs
  • 07:56Results: Characterization and In Vitro Evaluation as a Drug Delivery Platform of the Block Copolymer Based of Poly(ethylene glycol) and Poly(phenyl glycidyl ether)
  • 09:32Conclusion

Summary

Automatic Translation

生活在甲氧基聚乙二醇(MPEG-b -PPheGE)苯基缩水甘油醚(PheGE)的阴离子聚合的关键步骤进行说明。将所得嵌段共聚物胶束(带宽模型)的下生理学上得到有关条件装载阿霉素14%(重量%)和药物的持续释放超过4天。

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