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JoVE Journal
Immunology and Infection

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Assessing Retinal Microglial Phagocytic Function In Vivo Using a Flow Cytometry-based Assay
 

Assessing Retinal Microglial Phagocytic Function In Vivo Using a Flow Cytometry-based Assay

Article DOI: 10.3791/54677
October 18th, 2016

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Summary October 18th, 2016

Microglial phagocytosis is critical for the maintenance of tissue homeostasis and inadequate phagocytic function has been implicated in pathology. However, assessing microglia function in vivo is technically challenging. We have developed a simple but robust technique for precisely monitoring and quantifying the phagocytic potential of microglia in a physiological setting.

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