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JoVE Journal
Medicine

This content is Open Access.

Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model
 

Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model

Article doi: 10.3791/54729
April 2nd, 2017

Summary April 2nd, 2017

A unique rat liver hilar clamp model was developed for studying the impact of pharmacologic molecules in ameliorating ischemia-reperfusion injury. This model includes direct cannulation of the portal supply to the ischemic liver segment via a branch of the portal vein, allowing for direct hepatic delivery.

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