Journal
/
Cancer Research
/
临床前小鼠模型的外科手术和方法<em> De Novo</em>乳腺癌转移
JoVE Journal
Cancer Research
Author Produced
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Cancer Research
Surgical Procedures and Methodology for a Preclinical Murine Model of De Novo Mammary Cancer Metastasis
Please note that all translations are automatically generated. Click here for the English version.

临床前小鼠模型的外科手术和方法<em> De Novo</em>乳腺癌转移

DOI:
10.3791/54852-v

•

08:41 min

•

July 29, 2017

•

, , ,
1Cell, Developmental & Cancer Biology,Oregon Health & Science University, 2University of Minnesota, 3Knight Cancer Institute,Oregon Health & Science University

Chapters

  • 00:00Title
  • 00:30Introduction
  • 01:20Sterilization of Surgical Site
  • 02:06Primary Tumor Exposure
  • 03:15Removal of Primary Tumor
  • 06:06Wound Closure
  • 07:35Representative Results
  • 07:55Conclusion

Summary

Automatic Translation

Automatic Translation

评估靶向乳腺癌转移的辅助治疗的临床前模型缺乏。为了解决这个问题，我们开发了从头肺乳腺癌转移，其特征在于，在辅助设定（后手术切除原发肿瘤的）给药的治疗可以为疗效影响先前接种的肺转移进行评估的鼠模型。

Tags

Murine ModelMammary CancerMetastasisPreclinicalSurgical ResectionMMTV-PyMTOrthotopic InjectionPrimary TumorLung Metastasis

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

详细的定性C1498小鼠细胞系及其关联白血病小鼠模型协议

原发肿瘤发展小鼠实验模型和腹膜转移<em>通过</em>原位接种卵巢癌细胞

开发和维护的临床前患者来源的肿瘤异种移植模型为新的抗癌疗法的调查

在电化学疗法的操作程序在肿瘤治疗中的狗和猫

门静脉注射模型来研究肝转移乳腺癌

转移性的型号同源小鼠肾细胞癌的临床前疗法的定量和纵向评估

疲劳的小鼠模型的外围照射引起

乳腺癌细胞系外周血单核细胞破的人前临床模型的建立

通过实体瘤移植植入骨模拟原发性骨肿瘤和骨转移

斑马鱼神经母细胞瘤转移模型

Read Article