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JoVE Journal
Biology

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Chip-based Three-dimensional Cell Culture in Perfused Micro-bioreactors
 

Chip-based Three-dimensional Cell Culture in Perfused Micro-bioreactors

Article DOI: 10.3791/564
May 21st, 2008

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Summary May 21st, 2008

We describe a chip-based platform for the three-dimensional cultivation of cells in micro-bioreactors. One chip can house up to 10 Mio. cells that can be cultivated under precisely defined conditions with regard to fluid flow, oxygen tension etc. in a sterile, closed circulation loop.

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