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An Objective and Reproducible Test of Olfactory Learning and Discrimination in Mice
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Neuroscience
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JoVE Journal Neuroscience
An Objective and Reproducible Test of Olfactory Learning and Discrimination in Mice

An Objective and Reproducible Test of Olfactory Learning and Discrimination in Mice

DOI:
10.3791/57142-v

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09:33 min

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March 22, 2018

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, , , , , ,
1Program in Developmental Biology,Baylor College of Medicine, 2Medical Scientist Training Program,Baylor College of Medicine, 3Department of Neuroscience,Baylor College of Medicine, 4Department of Molecular and Human Genetics,Baylor College of Medicine, 5Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital

Chapters

  • 00:05Title
  • 01:02Construction and General Rules for Using Operant Learning Box
  • 03:14Mouse Preparation and Training
  • 07:22Results: Representative Results for Go/No-go Task
  • 08:32Conclusion

Summary

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Automatic Translation

Here, we train mice on an associative learning task to test odor discrimination. This protocol also allows for studies on learning-induced structural changes in the brain.

Tags

Olfactory LearningOlfactory DiscriminationMouse BehaviorOdor-reward AssociationOdor-punishment AssociationNeuroscienceOlfactionSensory DiscriminationNeurodegenerative DiseasesOlfactory DysfunctionCognitive DeclineBehavior ChamberOdor PortsOdor ValvesWater PortsWater ValvesAirflowUSB InterfaceWater Restriction

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