-1::1
Simple Hit Counter
Skip to content

Products

Solutions

×
×
Sign In

EN

EN - EnglishCN - 简体中文DE - DeutschES - EspañolKR - 한국어IT - ItalianoFR - FrançaisPT - Português do BrasilPL - PolskiHE - עִבְרִיתRU - РусскийJA - 日本語TR - TürkçeAR - العربية
Sign In Start Free Trial

RESEARCH

JoVE Journal

Peer reviewed scientific video journal

Behavior
Biochemistry
Bioengineering
Biology
Cancer Research
Chemistry
Developmental Biology
View All
JoVE Encyclopedia of Experiments

Video encyclopedia of advanced research methods

Biological Techniques
Biology
Cancer Research
Immunology
Neuroscience
Microbiology
JoVE Visualize

Visualizing science through experiment videos

EDUCATION

JoVE Core

Video textbooks for undergraduate courses

Analytical Chemistry
Anatomy and Physiology
Biology
Calculus
Cell Biology
Chemistry
Civil Engineering
Electrical Engineering
View All
JoVE Science Education

Visual demonstrations of key scientific experiments

Advanced Biology
Basic Biology
Chemistry
View All
JoVE Lab Manual

Videos of experiments for undergraduate lab courses

Biology
Chemistry

BUSINESS

JoVE Business

Video textbooks for business education

Accounting
Finance
Macroeconomics
Marketing
Microeconomics

OTHERS

JoVE Quiz

Interactive video based quizzes for formative assessments

Authors

Teaching Faculty

Librarians

K12 Schools

Biopharma

Products

RESEARCH

JoVE Journal

Peer reviewed scientific video journal

JoVE Encyclopedia of Experiments

Video encyclopedia of advanced research methods

JoVE Visualize

Visualizing science through experiment videos

EDUCATION

JoVE Core

Video textbooks for undergraduates

JoVE Science Education

Visual demonstrations of key scientific experiments

JoVE Lab Manual

Videos of experiments for undergraduate lab courses

BUSINESS

JoVE Business

Video textbooks for business education

OTHERS

JoVE Quiz

Interactive video based quizzes for formative assessments

Solutions

Authors
Teaching Faculty
Librarians
K12 Schools
Biopharma

Language

English

EN

English

CN

简体中文

DE

Deutsch

ES

Español

KR

한국어

IT

Italiano

FR

Français

PT

Português do Brasil

PL

Polski

HE

עִבְרִית

RU

Русский

JA

日本語

TR

Türkçe

AR

العربية

    Menu

    JoVE Journal

    Behavior

    Biochemistry

    Bioengineering

    Biology

    Cancer Research

    Chemistry

    Developmental Biology

    Engineering

    Environment

    Genetics

    Immunology and Infection

    Medicine

    Neuroscience

    Menu

    JoVE Encyclopedia of Experiments

    Biological Techniques

    Biology

    Cancer Research

    Immunology

    Neuroscience

    Microbiology

    Menu

    JoVE Core

    Analytical Chemistry

    Anatomy and Physiology

    Biology

    Calculus

    Cell Biology

    Chemistry

    Civil Engineering

    Electrical Engineering

    Introduction to Psychology

    Mechanical Engineering

    Medical-Surgical Nursing

    View All

    Menu

    JoVE Science Education

    Advanced Biology

    Basic Biology

    Chemistry

    Clinical Skills

    Engineering

    Environmental Sciences

    Physics

    Psychology

    View All

    Menu

    JoVE Lab Manual

    Biology

    Chemistry

    Menu

    JoVE Business

    Accounting

    Finance

    Macroeconomics

    Marketing

    Microeconomics

Start Free Trial
Loading...
Home
JoVE Journal
Engineering
Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter duri...
Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter duri...
JoVE Journal
Engineering
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Engineering
Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Full Text
8,566 Views
11:38 min
April 19, 2018

DOI: 10.3791/57429-v

Matthew D. Wehrman1, Melissa J. Milstrey1, Seth Lindberg2, Kelly M. Schultz1

1Department of Chemical and Biomolecular Engineering,Lehigh University, 2Process and Engineering Development,Procter & Gamble Co.

Overview

This study presents a microfluidic device designed for multiple particle tracking microrheology measurements. It focuses on understanding the rheological effects of repeated phase transitions in soft matter.

Key Study Components

Area of Science

  • Microfluidics
  • Soft Matter Physics
  • Rheology

Background

  • Microfluidics allows for precise control of fluid environments.
  • Phase transitions can significantly alter the properties of soft materials.
  • Multiple particle tracking microrheology provides insights into dynamic changes.
  • Real-time characterization is crucial for understanding complex systems.

Purpose of Study

  • To investigate the impact of phase transitions on rheological properties.
  • To enable real-time measurement of soft matter behavior.
  • To quantify unique rheological properties in heterogeneous systems.

Methods Used

  • Fabrication of a microfluidic device.
  • Inducing consecutive phase transitions by fluid exchange.
  • Measurement of rheological properties using multiple particle tracking.
  • Maintaining the sample in place during transitions for accurate data.

Main Results

  • Demonstrated the feasibility of the microfluidic device for rheological studies.
  • Showed how phase transitions affect the dynamic properties of soft matter.
  • Provided a method for real-time characterization of soft materials.
  • Quantified changes in rheological properties during phase transitions.

Conclusions

  • The microfluidic device is effective for studying soft matter rheology.
  • Real-time measurements enhance understanding of phase transition effects.
  • This approach can advance research in soft matter physics.

Frequently Asked Questions

What is the main advantage of using microfluidics in this study?
The main advantage is that the sample remains in place during multiple phase transitions, allowing for real-time characterization.
How does this method contribute to the field of soft matter?
It provides insights into the impact of phase transitions on dynamic rheological properties, which is crucial for understanding soft materials.
What are the key components of the microfluidic device?
The device is designed to facilitate fluid exchange and enable multiple particle tracking for rheological measurements.
Can this technique be applied to other materials?
Yes, the technique can be adapted to study various soft matter systems beyond those initially tested.
What are the implications of this research?
The findings can lead to better understanding and manipulation of soft materials in various applications.

We demonstrate the fabrication and use of a microfluidic device that enables multiple particle tracking microrheology measurements to study the rheological effects of repeated phase transitions on soft matter.

The overall goal of this procedure is to use microfluidics to induce consecutive phase transitions in a single soft matter sample by exchanging the surrounding fluid while simultaneously measuring changes in the rheological properties using multiple particle tracking microrheology. This method can answer key questions in the soft matter field, such as the impact of phase transitions, including molecular or colloidal rearrangement on dynamic rheological properties. This technique's main advantage is that the sample remains in place during multiple phase transitions, enabling real-time characterization.

This allows quantification of rheological properties, especially unique properties in heterogeneous systems. To begin the procedure, print the microfluidic device negative on a clear acetate sheet, and warm up a high-intensity UV lamp. On a second clear acetate sheet, trace the corners of a 75 millimeter by 50 millimeter slide.

View the full transcript and gain access to thousands of scientific videos

View the full transcript and gain access to thousands of scientific videos

Sign In Start Free Trial

Explore More Videos

MicrofluidicsMicrorheologySoft MatterPhase TransitionsRheological PropertiesHeterogeneous SystemsPDMSUV Curable ResinMicrofluidic Device Fabrication

Related Videos

Measuring Material Microstructure Under Flow Using 1-2 Plane Flow-Small Angle Neutron Scattering

09:08

Measuring Material Microstructure Under Flow Using 1-2 Plane Flow-Small Angle Neutron Scattering

Related Videos

14.8K Views

Controlled Microfluidic Environment for Dynamic Investigation of Red Blood Cell Aggregation

10:27

Controlled Microfluidic Environment for Dynamic Investigation of Red Blood Cell Aggregation

Related Videos

12.4K Views

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

10:12

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Related Videos

9.6K Views

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers

12:37

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers

Related Videos

13.1K Views

In Situ Mapping of the Mechanical Properties of Biofilms by Particle-tracking Microrheology

12:58

In Situ Mapping of the Mechanical Properties of Biofilms by Particle-tracking Microrheology

Related Videos

10.3K Views

Dielectric RheoSANS — Simultaneous Interrogation of Impedance, Rheology and Small Angle Neutron Scattering of Complex Fluids

07:51

Dielectric RheoSANS — Simultaneous Interrogation of Impedance, Rheology and Small Angle Neutron Scattering of Complex Fluids

Related Videos

10.9K Views

Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure

08:02

Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure

Related Videos

11.1K Views

Microfluidic Preparation of Liquid Crystalline Elastomer Actuators

12:04

Microfluidic Preparation of Liquid Crystalline Elastomer Actuators

Related Videos

9.5K Views

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal

06:24

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal

Related Videos

6.9K Views

Macro-Rheology Characterization of Gill Raker Mucus in the Silver Carp, Hypophthalmichthys molitrix

09:13

Macro-Rheology Characterization of Gill Raker Mucus in the Silver Carp, Hypophthalmichthys molitrix

Related Videos

3.6K Views

JoVE logo
Contact Us Recommend to Library
Research
  • JoVE Journal
  • JoVE Encyclopedia of Experiments
  • JoVE Visualize
Business
  • JoVE Business
Education
  • JoVE Core
  • JoVE Science Education
  • JoVE Lab Manual
  • JoVE Quizzes
Solutions
  • Authors
  • Teaching Faculty
  • Librarians
  • K12 Schools
  • Biopharma
About JoVE
  • Overview
  • Leadership
Others
  • JoVE Newsletters
  • JoVE Help Center
  • Blogs
  • JoVE Newsroom
  • Site Maps
Contact Us Recommend to Library
JoVE logo

Copyright © 2026 MyJoVE Corporation. All rights reserved

Privacy Terms of Use Policies
WeChat QR code