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Genetics

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JoVE Journal Genetics
Using Mouse Oocytes to Assess Human Gene Function During Meiosis I
 

Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

Article doi: 10.3791/57442
April 10th, 2018 •
*1,2, *3, 1,2, 3
1IVI-RMA New Jersey, 2Jefferson College of Biomedical Sciences, Thomas Jefferson University, 3Department of Genetics, Rutgers, The State University of New Jersey
* These authors contributed equally

Summary
Automatic Translation
April 10th, 2018

As the genetic variants associated with human disease begin to become uncovered, it is becoming increasingly important to develop systems with which to rapidly evaluate the biological significance of those identified variants. This protocol describes methods for evaluating human gene function during female meiosis I using mouse oocytes.

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