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Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation
Bioprintable Alginate/Gelatin Hydrogel 3D <em>In Vitro</em> Model Systems Induce Cell Spheroid Formation
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation

Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation

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16:20 min

July 02, 2018

DOI:

16:20 min
July 02, 2018

18560 Views
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We developed a heterogeneous breast cancer model consisting of immortalized tumor and fibroblast cells embedded in a bioprintable alginate/gelatin bioink. The model recapitulates the in vivo tumor microenvironment and facilitates the formation of multicellular tumor spheroids, yielding insight into the mechanisms driving tumorigenesis.

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