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Journal / Immunology and Infection / Stereotactic adoptivforeldre overføring av…
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Immunology and Infection
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JoVE Journal Immunology and Infection
Stereotactic adoptivforeldre overføring av cytotoksiske immunceller i Murine modeller av Orthotopic Human Glioblastoma Multiforme Xenografts
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Stereotactic adoptivforeldre overføring av cytotoksiske immunceller i Murine modeller av Orthotopic Human Glioblastoma Multiforme Xenografts

Article DOI: 10.3791/57870-v • 11:16 min • September 1st, 2018
September 1st, 2018 •
*1,2, *1,2, *1,2, 1,2,3, 1,2, 1,2
1INSERM, CNRS, Université d'Angers, Université de Nantes, CRCINA, 2Immunotherapy, Graft, Oncology, LabEx IGO, 3Hopital de Nantes, Hotel Dieu
* These authors contributed equally

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Her presenterer vi en protokoll for utarbeidelse og stereotaxic administrasjonen av allogene menneskelige lymfocytter i immunodeficient mus bærer orthotopic primære hjernesvulster. Denne studien gir en proof-of-concept for både gjennomførbarhet og antitumor effekten av intrabrain-levert mobilnettet immunotherapies.

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Immunologi og infeksjon problemet 139 kreft glioblastom immunterapi adopsjon overføring stereotaxy lymfocytter
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