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Vurdering af ultrastrukturelle neuroplasticitet parametre efter i Utero transduktion af udvikle mus hjernen og rygmarven
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Developmental Biology
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JoVE Journal Developmental Biology
Assessment of Ultrastructural Neuroplasticity Parameters After In Utero Transduction of the Developing Mouse Brain and Spinal Cord

Vurdering af ultrastrukturelle neuroplasticitet parametre efter i Utero transduktion af udvikle mus hjernen og rygmarven

DOI:
10.3791/59084-v

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10:28 min

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February 26, 2019

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, , , , , ,
1Department of Neuroanatomy and Molecular Brain Research,Ruhr University Bochum, 2Central Animal Facility of the Medical Faculty,Ruhr University Bochum

Chapters

  • 00:04Title
  • 01:22In Utero Transduction
  • 03:13Telemacrophotographic Imaging
  • 04:12Transmission Electron Microscopy Tissue Preparation
  • 06:13Ultrastructural Neuroplasticity Parameter Selection
  • 07:44Results: Representative Ultrastructural Imaging of In Utero-Transduced Mouse Embryonic Tissues
  • 09:23Conclusion

Summary

Automatic Translation

Automatic Translation

Kombinationen af transmissions elektronmikroskopi og i livmoderen transduktion er en kraftfuld tilgang til at studere morfologiske ændringer i den fine ultrastruktur af nervesystemet under udvikling. Denne kombinerede metode giver dyb indsigt i ændringer i strukturelle detaljer underliggende neuroplasticitet med hensyn til deres topografiske repræsentation.

Tags

Ultrastructural NeuroplasticityIn Utero TransductionMouse BrainSpinal CordCongenital Neurodegenerative DiseasesAdeno-associated VirusEmbryonic DevelopmentElectron Microscopy

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