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Immunology and Infection

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JoVE Journal Immunology and Infection
Un modelo murino de enfermedad similar a la encefalitis vírica aguda inducida por el virus del dengue
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Un modelo murino de enfermedad similar a la encefalitis vírica aguda inducida por el virus del dengue

Article DOI: 10.3791/59132-v • 04:23 min • April 28th, 2019
April 28th, 2019 •
1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2,3
1Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, 2Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, 3Center of Infectious Disease and Signaling Research, National Cheng Kung University

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Aquí, presentamos un protocolo para crear un modelo murino irevolucionario inmunocompetente (Instituto de Investigación del Cáncer) de infección del sistema nervioso central para mostrar el desarrollo de la neuropatía. El control de trastornos encefalíticos víricos agudos por puntuaciones idénticas de enfermedad podría realizarse para mostrar in vivo la neuropatía inducida por el virus del dengue.

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Inmunología e infección número 146 murina virus del dengue encefalitis neurotoxicidad inyección intracerebral inyección intraperitoneal ratones chupadores
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