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JoVE Journal
Immunology and Infection

This content is Open Access.

A Positioning Device for the Placement of Mice During Intranasal siRNA Delivery to the Central Nervous System
 

A Positioning Device for the Placement of Mice During Intranasal siRNA Delivery to the Central Nervous System

Article DOI: 10.3791/59201
August 15th, 2019

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Summary August 15th, 2019

Here, we present a protocol using a mouse positioning device that enables the appropriate placement of mice for the intranasal administration of a brain-targeting peptide-siRNA formulation enabling effective gene silencing in the central nervous system.

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