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Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice
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Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice

Article DOI: 10.3791/59431-v • 09:40 min • May 13th, 2019
May 13th, 2019 •
1, 1, 1, 2, 1, 1, 1
1Department of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, 2The Third Clinical Medical College, Guangzhou Medical University

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Summary
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Here, we provide a useful approach for studying the mechanism of right ventricular failure. A more convenient and efficient approach to pulmonary artery constriction is established using surgical instruments made inhouse. In addition, methods to evaluate the quality of this approach by echocardiography and catheterization are provided.

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Right Ventricular Failure Pulmonary Artery Constriction Right Ventricular Function Mice Technique Surgery Time-saving Success Rate Pulmonary Artery Constriction Pulmonate Pressure Overload Transverse Aortic Constriction Technique Post Heart Transplantation Complications Congenital Heart Disease Studies Xiaoxia Huang Technician Braided Silk Suture Needle Disassembled From A One Milliliter Syringe Hemostatic Forceps Heating Pad Anesthetized Mouse Supine Position Incisors Suture Tape Depilatory Cream Neck To Xiphoid Process Iodine Wipes Ethanol Wipes Pointed Pliers
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