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Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice
JoVE Journal
Biology
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JoVE Journal Biology
Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice
DOI:

09:40 min

May 13, 2019

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Chapters

  • 00:04Title
  • 00:57Surgical Preparation
  • 02:44Pulmonary Artery Constriction
  • 04:30Echocardiographic Right Ventricle (RV) Function Assessment
  • 06:06Right Heart Catheterization RV Function Assessment
  • 07:20Results: Representative Cardiac Functional and Morphological Assessment After Pulmonary Artery Construction
  • 08:55Conclusion

Summary

Automatic Translation

Here, we provide a useful approach for studying the mechanism of right ventricular failure. A more convenient and efficient approach to pulmonary artery constriction is established using surgical instruments made inhouse. In addition, methods to evaluate the quality of this approach by echocardiography and catheterization are provided.

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