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黑色素瘤患者衍生异种移植模型
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
A Melanoma Patient-Derived Xenograft Model
DOI:

07:07 min

May 20, 2019

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Chapters

  • 00:04Title
  • 00:39Tumor Tissue Processing for Mouse Implantation
  • 02:42Tumor Implantation and Injection in Mice
  • 04:07Tumor Harvesting for Banking Tissue, Reimplantation, and Experiment Characterization
  • 05:30Results: Analysis of Melanoma Patient-Derived Xenograft Models
  • 06:18Conclusion

Summary

Automatic Translation

与传统的基于塑料组织培养的检测相比,患者衍生的异种移植 (PDX) 模型更有力地概括黑色素瘤分子和生物特征,并更预测治疗反应。在这里,我们描述了我们用于建立新的 PDX 模型的标准操作协议,以及现有 PDX 模型的特征/实验。

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