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Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson’s Disease
JoVE Journal
Behavior
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JoVE Journal Behavior
Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson’s Disease

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson’s Disease

DOI:
10.3791/59827-v

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10:28 min

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July 24, 2019

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, , ,
1Department of Psychology,Rutgers University, 2Rutgers University Center for Cognitive Science,Rutgers University, 3Rutgers-Robert Wood Johnson Medical School, Department of Psychiatry,Rutgers University, 4Center for Biomedicine, Imaging and Modelling, Department of Computer Science,Rutgers University

Chapters

  • 00:04Title
  • 01:29Participant Preparation and Acquisition System Setup
  • 04:29Experimental Procedure
  • 07:47Results: Representative Dynamic Digital Biomarker Analyses
  • 09:43Conlcusion

Summary

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This protocol offers a digitization of portions of traditional clinical tasks commonly used to measure cognition and motor control in Parkinson’s disease. Clinical tasks are digitized while biophysical rhythms are co-registered from different functional levels of the nervous systems, ranging from voluntary, spontaneous, automatic to autonomic.

Tags

Parkinson’s DiseaseDigital BiomarkersWearable SensorsCognitionMotionEmotionNeurological DisordersPersonalized MedicineStatistical VariabilityMotion CaptureEEGBiosensors

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