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Solid Phase 11C-Methylation, Purification and Formulation for the Production of PET Tracers
 

Solid Phase 11C-Methylation, Purification and Formulation for the Production of PET Tracers

Article doi: 10.3791/60237
October 24th, 2019

Summary October 24th, 2019

We report an efficient carbon-11 radiolabeling technique to produce clinically relevant tracers for Positron Emission Tomography (PET) using solid phase extraction cartridges. 11C-methylating agent is passed through a cartridge preloaded with precursor and successive elution with aqueous ethanol provides chemically and radiochemically pure PET tracers in high radiochemical yields.

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