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Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration
Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration

Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration

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10:53 min

October 13, 2019

DOI:

10:53 min
October 13, 2019

6993 Views
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Summary

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Collective cell migration in development, wound healing, and cancer metastasis is often guided by the gradients of growth factors or signaling molecules. Described here is an experimental system combining traction microscopy with a microfluidic system and a demonstration of how to quantify the mechanics of collective migration under biochemical gradient.

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