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JoVE Journal
Bioengineering

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Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration
 

Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration

Article doi: 10.3791/60415
October 13th, 2019

Summary October 13th, 2019

Collective cell migration in development, wound healing, and cancer metastasis is often guided by the gradients of growth factors or signaling molecules. Described here is an experimental system combining traction microscopy with a microfluidic system and a demonstration of how to quantify the mechanics of collective migration under biochemical gradient.

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