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JoVE Journal
Bioengineering

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Planar Gradient Diffusion System to Investigate Chemotaxis in a 3D Collagen Matrix
 

Planar Gradient Diffusion System to Investigate Chemotaxis in a 3D Collagen Matrix

Article doi: 10.3791/52948
June 12th, 2015

Summary June 12th, 2015

Cell migration is an important part of human development and life. In order to understand the mechanisms that can alter cell migration, we present a planar gradient diffusion system to investigate chemotaxis in a 3D collagen matrix, which allows one to overcome modern diffusion chamber limitations of existing assays.

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