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JoVE Journal
Immunology and Infection

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Stabilitet och struktur av Fladdermus Major Histocompatibility Complex Klass I med heterologous β2-Microglobulin
 
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Stabilitet och struktur av Fladdermus Major Histocompatibility Complex Klass I med heterologous β2-Microglobulin

Article DOI: 10.3791/61462-v
March 10th, 2021

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Summary March 10th, 2021

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Protokollet beskriver experimentella metoder för att erhålla stabila stora histocompatibility komplexa (MHC) klass I genom potentiella β2-mikroglobulin2m) substitutioner från olika arter. Den strukturella jämförelsen av MHC jag stabiliseras av homologa och heterologa β2m undersöktes.

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