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Crystallization of Proteins on Chip by Microdialysis for In Situ X-ray Diffraction Studies
 

Crystallization of Proteins on Chip by Microdialysis for In Situ X-ray Diffraction Studies

Article doi: 10.3791/61660
April 11th, 2021

Summary April 11th, 2021

This paper details the fabrication protocol of microfluidic chips developed for on-chip protein crystallization with the dialysis method and in situ X-ray diffraction experiments. The microfabrication process makes it possible to integrate a semipermeable regenerated cellulose dialysis membrane with any molecular weight cut-off, between two layers of the chip.

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