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Journal / Biology / 使用BrdU-DNA标记结合细胞周期鉴别成像评估全球DNA双链末端切除术…
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使用BrdU-DNA标记结合细胞周期鉴别成像评估全球DNA双链末端切除术
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使用BrdU-DNA标记结合细胞周期鉴别成像评估全球DNA双链末端切除术

Article DOI: 10.3791/62553-v • 06:44 min • April 28th, 2021
April 28th, 2021 •
*1,2, *1,2, 2,3, 1,2
1Oncology Division, Genome Stability Laboratory, CHU de Québec Research Center, HDQ Pavilion, 2Department of Molecular Biology, Medical Biochemistry, and Pathology, Laval University Cancer Research Center, 3Oncology Division, CHU de Québec Research Center, CHUL Pavilion
* These authors contributed equally

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在本方案中，我们展示了如何使用基于免疫荧光的方法在细胞周期的S / G2阶段可视化DNA双链末端切除。

Tags

生物学，第170期，BrdU病灶，免疫荧光，DNA末端切除，同源重组，PARP-1，PARP抑制剂，PARP抑制剂耐药性，BMN673
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