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Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
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Chapters
- 00:05Introduction
- 00:36Dural Infuser
- 02:12Dural Injections
- 03:11Periorbital von Frey
- 04:14Results: Dural Prolactin Stimulation in Mice as a Preclinical Headache Model
- 05:07Conclusion
The most notable symptom of migraine is severe head pain, and it is hypothesized that this is mediated by sensory neurons innervating the meninges. Here, we present a method to locally apply substances to the dura in a minimally invasive manner while using facial hypersensitivity as an output.
