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Journal / Cancer Research / 간세포 암에서 종양-기질 상호 작용을 조사하는 3차원 스페로이드…
JoVE Journal
Cancer Research

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JoVE Journal Cancer Research
간세포 암에서 종양-기질 상호 작용을 조사하는 3차원 스페로이드 모델
High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor
Journal (Cancer Research)
High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor
Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice
Journal (Cancer Research)
Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice
 
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간세포 암에서 종양-기질 상호 작용을 조사하는 3차원 스페로이드 모델

Article DOI: 10.3791/62868-v • 12:24 min • September 30th, 2021
September 30th, 2021 •
*1,2, *2, 2, 2, *3, *4,5
1Department of Biochemistry, Faculty of Pharmacy, Minia University, 2National Institute for Health Research Birmingham Liver Biomedical Research Unit and Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, 3Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, 4Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, 5The Liver Unit, Department of Medicine, Freeman Hospital, Newcastle-upon-Tyne Hospitals NHS Foundation Trust
* These authors contributed equally

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관련 인간 질병을 충실하게 재구성하는 포괄적인 체외 모델은 부족합니다. 현재 연구는 인간 간세포 암에서 종양 기질 상호 작용을 연구하는 신뢰할 수있는 체외 도구인 3차원 (3D) 종양 스페로이드 생성 및 문화를 제시합니다.

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암 연구 문제 175
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