Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence

5.1K views

Cited by 7

14:55 min

March 5th, 2022

10.3791/63095-v

March 5th, 2022

5.1K views

Alyson Nguyen^*¹ , Keith Battle^*²^,³ , Sunita S. Paudel^*²^,³ , Ningyong Xu² , Jessica Bell³ , Linn Ayers³ , Cassandra Chapman⁴ , Ajay P. Singh⁵ , Srinivas Palanki⁶ , Thomas Rich³^,⁷ , Diego F. Alvarez⁸ , Troy Stevens²^,³ , Dhananjay T. Tambe³^,⁴^,⁷

¹Biomedical Sciences, Pat Capps Covey College of Allied Health Professions, University of South Alabama, ²Department of Physiology and Cell Biology, College of Medicine, University of South Alabama, ³Center for Lung Biology, College of Medicine, University of South Alabama, ⁴William B. Burnsed Jr. Mechanical, Aerospace, and Biomedical Engineering Department, College of Engineering, University of South Alabama, ⁵Mitchell Cancer Institute, College of Medicine, University of South Alabama, ⁶Department of Chemical and Biomedical Engineering, West Virginia University, ⁷Department of Pharmacology, College of Medicine, University of South Alabama, ⁸Department of Physiology & Pharmacology, College of Osteopathic Medicine, Sam Houston State University

^* These authors contributed equally

The Integrative Toolkit to Analyze Cellular Signals (iTACS) platform automates the process of simultaneously measuring a wide variety of chemical and mechanical signals in adherent cells. iTACS is designed to facilitate community-driven development and enable researchers to use all platform features regardless of their educational background.