JoVE Journal
Neuroscience
Neuroscience
A subscription to JoVE is required to view this content.
Chapters
Summary
Oxygen consumption rate (OCR) is a common proxy for mitochondrial function and can be used to study different disease models. We developed a new method using a Seahorse XF analyzer to directly measure the OCR in acute striatal slices from adult mice that is more physiologically relevant than other methods.