Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Ming Wang; Shuyi Zhang; Wanling Han; Maoqing Ye; Xinkai Qu; Wenzheng Han

doi:10.3791/63719

Journal

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Medicine

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Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

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Medicine

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JoVE Journal Medicine

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

2,980 Views

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08:35 min

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May 26, 2022

DOI:

10.3791/63719-v

DOI:

10.3791/63719-v

•

08:35 min

May 26, 2022

•

20 Views

Ming Wang*^1,2, Shuyi Zhang*^1,2, Wanling Han^1,2, Maoqing Ye^1,2, Xinkai Qu^1,2, Wenzheng Han^1,2

¹Department of Cardiology,Huadong Hospital Affiliated to Fudan University, ²Shanghai Key Laboratory of Clinical Geriatric Medicine

Summary

Here, we present a protocol for renal sympathetic denervation (RDN) in mice with hypertension induced by Angiotensin II infusion. The procedure is repeatable, convenient and allows to study the regulatory mechanisms of RDN on hypertension and cardiac hypertrophy.