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Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
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Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

DOI:
10.3791/63719-v

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08:35 min

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May 26, 2022

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, , , , ,
1Department of Cardiology,Huadong Hospital Affiliated to Fudan University, 2Shanghai Key Laboratory of Clinical Geriatric Medicine

Chapters

  • 00:05Introduction
  • 00:42Preparation of the Operation Field
  • 01:18Angiotensin II Induced Hypertension
  • 03:21Bilateral Renal Denervation
  • 05:33Results: Renal Sympathetic Denervation (RDN) in Mice with Hypertension Induced by Angiotensin II Infusion
  • 07:41Conclusion

Summary

Automatic Translation

Automatic Translation

Here, we present a protocol for renal sympathetic denervation (RDN) in mice with hypertension induced by Angiotensin II infusion. The procedure is repeatable, convenient and allows to study the regulatory mechanisms of RDN on hypertension and cardiac hypertrophy.

Tags

Keywords: Renal DenervationHypertensionAngiotensin II InfusionOsmotic PumpTail-cuff PlethysmographySurgical ProcedureC57BKL/6 MouseBlood Pressure Monitoring

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