Journal
/
Medicine
/
Ameliorating Osteoarthritis in Mice Using Silver Nanoparticles
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal Medicine
Ameliorating Osteoarthritis in Mice Using Silver Nanoparticles

Ameliorating Osteoarthritis in Mice Using Silver Nanoparticles

DOI:
10.3791/65111-v

•

05:50 min

•

June 02, 2023

•

, , , , , , , ,
1Department of Orthopedics,The Third Affiliated Hospital of Sun Yat-sen University

Chapters

  • 00:00Introduction
  • 00:44Knee Osteoarthritis (KOA) Mouse Model Establishment
  • 01:41Synthesis of Silver Nanoparticle and Treatment of Collagenase‐Induced KOA Mice
  • 03:10Staining of the Collected Knee Joint and Synovial Tissue
  • 03:55Results: Comparative Analysis of KOA and Silver Nanoparticle‐Treated Murine Groups
  • 05:24Conclusion

Summary

Automatic Translation

Automatic Translation

Presented here is a protocol for using silver nanoparticles to effectively ameliorate the acute symptoms of type II collagenase-induced osteoarthritis mice, including synovial inflammation, synovial hyperplasia, vascular hyperplasia, etc.

Tags

Keywords: Silver NanoparticlesOsteoarthritisKnee JointCollagenaseType 1 CollagenSurgical ProcedureAnimal ExperimentationJoint InjectionInflammation

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/65111?article_type=v

The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse
check_url/65111?article_type=v

Using In Vitro Live-cell Imaging to Explore Chemotherapeutics Delivered by Lipid-based Nanoparticles
check_url/65111?article_type=v

Osteoarthritis Pain Model Induced by Intra-Articular Injection of Mono-Iodoacetate in Rats
check_url/65111?article_type=v

Sleeve Gastrectomy in Mice using Surgical Clips
check_url/65111?article_type=v

Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
check_url/65111?article_type=v

Author Spotlight: Investigating Early Events and Long-Term Effects of ACL Injuries for Osteoarthritis Progression
check_url/65111?article_type=v

Author Spotlight: Investigating the Mechanism of Action of Acupotomy in Treating Knee Osteoarthritis
check_url/65111?article_type=v

Using a Rabbit Model to Explore the Efficacy of Tuina in Treating Knee Osteoarthritis (Video) | JoVE
check_url/65111?article_type=v

Treating Knee Osteoarthritis with Tuina - A New Perspective (Video) | JoVE
check_url/65111?article_type=v

Performing Fu's Subcutaneous Needling for Degenerative Knee Osteoarthritis (Video) | JoVE

Read Article