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JoVE Journal
Bioengineering

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人诱导多能干细胞分化为具有成熟免疫表型的脑微血管内皮细胞样细胞
 
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人诱导多能干细胞分化为具有成熟免疫表型的脑微血管内皮细胞样细胞

Article DOI: 10.3791/65134-v 09:03 min May 19th, 2023
May 19th, 2023

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Summary

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在这里,我们描述了一种协议,即扩展内皮细胞培养方法(EECM),该方法允许多能干细胞分化为脑微血管内皮细胞(BMEC)样细胞。这些细胞表现出内皮细胞粘附分子表达,因此是适合在体外研究免疫细胞相互作用的人血脑屏障模型。

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