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Journal
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Behavior
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Validating a Murine Model of Angelman Syndrome Using Behavioral Tests
/
安格曼综合征小鼠模型的行为表征
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Behavior
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JoVE Journal
Behavior
Behavioral Characterization of an Angelman Syndrome Mouse Model
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安格曼综合征小鼠模型的行为表征
Validating a Murine Model of Angelman Syndrome Using Behavioral Tests
DOI:
10.3791/65182-v
•
01:48 min
•
October 20, 2023
•
Agnieszka Kubik-Zahorodna
,
Jan Prochazka
2
,
Radislav Sedlacek
2
1
Czech Centre for Phenogenomics
,
Institute of Molecular Genetics of the Czech Academy of Sciences
,
2
Laboratory of Transgenic Models of Diseases
,
Institute of Molecular Genetics of the Czech Academy of Sciences
Tags
Keywords: Angelman Syndrome
Mouse Model
Behavioral Characterization
CRISPR
UBE3A
Motor Impairment
Gait Analysis
Nest Building
Emotionality
Open Field
Elevated Plus Maze
Tail Suspension Test
Reproducibility
Validation
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