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October 06, 2023
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Summary
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Presented here is a new version of expansion microscopy (ExM), Magnify, that is modified for up to 11-fold expansion, conserving a comprehensive array of biomolecule classes, and is compatible with a broad range of tissue types. It enables the interrogation of the nanoscale configuration of biomolecules using conventional diffraction-limited microscopes.
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Cite this Article
Gallagher, B. R., Klimas, A., Cheng, Z., Zhao, Y. Universal Molecular Retention with 11-Fold Expansion Microscopy. J. Vis. Exp. (200), e65338, doi:10.3791/65338 (2023).
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