Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

Guanzhou Lin; Jia Zhu; Yang Wang; Bingquan Yang; Shisong Xiong; Jinwen Zhang; Wengang Wu

doi:10.3791/65595

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Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

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Engineering

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JoVE Journal Engineering

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

2,099 Views

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03:33 min

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November 17, 2023

DOI:

10.3791/65595-v

DOI:

10.3791/65595-v

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03:33 min

November 17, 2023

•

41 Views

Guanzhou Lin¹, Jia Zhu², Yang Wang¹, Bingquan Yang^1,3, Shisong Xiong^1,3, Jinwen Zhang¹, Wengang Wu¹

¹National Key Laboratory of Advanced Micro and Nano Manufacture Technology, School of Integrated Circuits,Peking University, ²School of Electronic Engineering and Computer Science,Peking University, ³School of Software and Microelectronics,Peking University

Transcript

This protocol describes preparing SERS flexible substrates, applying them to actual detection scenarios. The SERS flexible substrate offered by this protocol is environmental friendly and achieves good detection performance. The silver nanoparticles can be synthesized easily by simple vessels, and do not require complicated experimental conditions and environment.

In our laboratory, we plan to focus on researching the silver nanoparticles synthesized through the vessel used in this study. We’ll explore methods to enhance their SERS detection capabilities, and leverage their unique properties and characteristics to design better performing SERS detection substrates.

Summary

This protocol describes a fabrication method for a flexible substrate for surface-enhanced Raman scattering. This method has been used in the successful detection of low concentrations of R6G and Thiram.