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In Vivo 2-Photon Calcium Imaging in Layer 2/3 of Mice

Article DOI: 10.3791/681 • 08:11 min
March 13th, 2008 •
1, 1
1Department of Neurology, University of California, Los Angeles

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March 13th, 2008

To understand network dynamics of microcircuits in the neocortex, it is essential to simultaneously record the activity of a large number of neurons . In-vivo two-photon calcium imaging is the only method that allows one to record the activity of a dense neuronal population with single-cell resolution .

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