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Articles by Adrian C. Shieh in JoVE

 JoVE Bioengineering

Three-dimensional Cell Culture Model for Measuring the Effects of Interstitial Fluid Flow on Tumor Cell Invasion


JoVE 4159 7/25/2012

School of Biomedical Engineering, Science and Health Systems, Drexel University

Interstitial fluid flow is elevated in solid tumors and can modulate tumor cell invasion. Here we describe a technique to apply interstitial fluid flow to cells embedded in a matrix and then measure its effects on cell invasion. This technique can be easily adapted to study other systems.

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