Chandan K. Sen Indiana Center for Regenerative Medicine & Engineering, Indiana University Health Comprehensive Wound Center, Department of Surgery Indiana University School of Medicine Biography Publications Institution JoVE Articles Chandan K. Sen has not added a biography. If you are Chandan K. Sen and would like to personalize this page please email our Author Liaison for assistance. Publications Bacterial Pyocyanin Inducible KRT6A Accelerates Closure of Epithelial Defect The Journal of Investigative Dermatology. Apr, 2023 | Pubmed ID: 37044260 A Prospective, Randomized, Controlled Study to Evaluate the Effectiveness of a Fabric-Based Wireless Electroceutical Dressing Compared to Standard-of-Care Treatment Against Acute Trauma and Burn Wound Biofilm Infection Advances in Wound Care. Apr, 2023 | Pubmed ID: 36855334 Identification of a Physiologic Vasculogenic Fibroblast State to Achieve Tissue Repair Nature Communications. Feb, 2023 | Pubmed ID: 36854749 Inducible MiR-1224 Silences Cerebrovascular Serpine1 and Restores Blood Flow to the Stroke-affected Site of the Brain Molecular Therapy. Nucleic Acids. Mar, 2023 | Pubmed ID: 36726407 Adult Skin Fibroblast State Change in Murine Wound Healing Scientific Reports. Jan, 2023 | Pubmed ID: 36650180 Tissue Nanotransfection Causes Tumor Regression by Its Effect on Nanovesicle Cargo That Alters Microenvironmental Macrophage State Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2023 | Pubmed ID: 36380587 Driving Adult Tissue Repair Via Re-engagement of a Pathway Required for Fetal Healing Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2023 | Pubmed ID: 36114673 The NIDDK Diabetic Foot Consortium Journal of Diabetes Science and Technology. Jan, 2023 | Pubmed ID: 36059271 Diabetic Peripheral Neuropathy Associated with Foot Ulcer: One of a Kind Antioxidants & Redox Signaling. Jan, 2023 | Pubmed ID: 35850520 Epigenetic Basis of Diabetic Vasculopathy Frontiers in Endocrinology. 2022 | Pubmed ID: 36568089 Modeling the Gene Delivery Process of the Needle Array-based Tissue Nanotransfection Nano Research. Apr, 2022 | Pubmed ID: 36275042 Myogenic Tissue Nanotransfection Improves Muscle Torque Recovery Following Volumetric Muscle Loss NPJ Regenerative Medicine. Oct, 2022 | Pubmed ID: 36266362 Sex As Biological Variable in Cardiac Mitochondrial Bioenergetic Responses to Acute Stress International Journal of Molecular Sciences. Aug, 2022 | Pubmed ID: 36012574 Lysosomal Acid Lipase, CSF1R, and PD-L1 Determine Functions of CD11c+ Myeloid-derived Suppressor Cells JCI Insight. Sep, 2022 | Pubmed ID: 35917184 Genome-wide DNA Hypermethylation Opposes Healing in Patients with Chronic Wounds by Impairing Epithelial-mesenchymal Transition The Journal of Clinical Investigation. Sep, 2022 | Pubmed ID: 35819852 Exosomal Transfer of DNA Methyl-Transferase MRNA Induces an Immunosuppressive Phenotype in Human Monocytes Shock (Augusta, Ga.). Jun, 2022 | Pubmed ID: 35759303 Analysis of Keratinocytic Exosomes from Diabetic and Nondiabetic Mice by Charge Detection Mass Spectrometry Analytical Chemistry. Jun, 2022 | Pubmed ID: 35699514 Endothelial Phospholipase Cγ2 Improves Outcomes of Diabetic Ischemic Limb Rescue Following VEGF Therapy Diabetes. May, 2022 | Pubmed ID: 35192691 Laser Capture Microdissection in the Spatial Analysis of Epigenetic Modifications in Skin: A Comprehensive Review Oxidative Medicine and Cellular Longevity. 2022 | Pubmed ID: 35186184 Myo-Inositol in Fermented Sugar Matrix Improves Human Macrophage Function Molecular Nutrition & Food Research. Apr, 2022 | Pubmed ID: 35073444 Bone Marrow- or Adipose-mesenchymal Stromal Cell Secretome Preserves Myocardial Transcriptome Profile and Ameliorates Cardiac Damage Following Ex Vivo Cold Storage Journal of Molecular and Cellular Cardiology. Mar, 2022 | Pubmed ID: 34774548 Immediate Lymphatic Reconstruction to Prevent Breast Cancer-Related Lymphedema: A Systematic Review Advances in Wound Care. Jul, 2022 | Pubmed ID: 34714158 Oncostatin M Improves Cutaneous Wound Re-Epithelialization and Is Deficient Under Diabetic Conditions The Journal of Investigative Dermatology. Mar, 2022 | Pubmed ID: 34534575 Fabrication and Use of Silicon Hollow-needle Arrays to Achieve Tissue Nanotransfection in Mouse Tissue in Vivo Nature Protocols. Dec, 2021 | Pubmed ID: 34837085 Modeling Acute and Chronic Vascular Responses to a Major Arterial Occlusion Microcirculation (New York, N.Y. : 1994). Nov, 2021 | Pubmed ID: 34779082 Electroceutical Fabric Lowers Zeta Potential and Eradicates Coronavirus Infectivity Upon Contact Scientific Reports. Nov, 2021 | Pubmed ID: 34741051 Ketoconazole Resistant Candida Albicans is Sensitive to a Wireless Electroceutical Wound Care Dressing Bioelectrochemistry (Amsterdam, Netherlands). Dec, 2021 | Pubmed ID: 34419917 Biofilm Management in Wound Care Plastic and Reconstructive Surgery. Aug, 2021 | Pubmed ID: 34398099 The Hyperglycemia Stranglehold Stifles Cutaneous Epithelial‒Mesenchymal Plasticity and Functional Wound Closure The Journal of Investigative Dermatology. Jun, 2021 | Pubmed ID: 34024339 Multiplexed Signal Ion Emission Reactive Release Amplification (SIERRA) Assay for the Culture-Free Detection of Gram-Negative and Gram-Positive Bacteria and Antimicrobial Resistance Genes Analytical Chemistry. May, 2021 | Pubmed ID: 33819029 Nanotransfection-based Vasculogenic Cell Reprogramming Drives Functional Recovery in a Mouse Model of Ischemic Stroke Science Advances. Mar, 2021 | Pubmed ID: 33741587 A Surfactant Polymer Wound Dressing Protects Human Keratinocytes from Inducible Necroptosis Scientific Reports. Feb, 2021 | Pubmed ID: 33623080 Cutaneous Manifestations of COVID-19: A Systematic Review Advances in Wound Care. 02, 2021 | Pubmed ID: 33035150 Mitochondria As Target for Tumor Management of Hemangioendothelioma Antioxidants & Redox Signaling. 01, 2021 | Pubmed ID: 32597200 High Resolution Ultrasound Imaging for Repeated Measure of Wound Tissue Morphometry, Biomechanics and Hemodynamics Under Fetal, Adult and Diabetic Conditions PloS One. 2020 | Pubmed ID: 33227015 Urolithin A Augments Angiogenic Pathways in Skeletal Muscle by Bolstering NAD and SIRT1 Scientific Reports. 11, 2020 | Pubmed ID: 33214614 Ad Hoc Hybrid Synaptic Junctions to Detect Nerve Stimulation and Its Application to Detect Onset of Diabetic Polyneuropathy Biosensors & Bioelectronics. Dec, 2020 | Pubmed ID: 33007616 Exosome-Mediated Crosstalk Between Keratinocytes and Macrophages in Cutaneous Wound Healing ACS Nano. 10, 2020 | Pubmed ID: 32931251 Platelet Function in Stroke/transient Ischemic Attack Patients Treated with Tocotrienol FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2020 | Pubmed ID: 32686874 N-acetylcysteine Differentially Regulates the Populations of Bone Marrow and Circulating Endothelial Progenitor Cells in Mice with Limb Ischemia European Journal of Pharmacology. Aug, 2020 | Pubmed ID: 32492379 Electroceutical Management of Bacterial Biofilms and Surgical Infection Antioxidants & Redox Signaling. 10, 2020 | Pubmed ID: 32466673 Neurogenic Tissue Nanotransfection in the Management of Cutaneous Diabetic Polyneuropathy Nanomedicine : Nanotechnology, Biology, and Medicine. 08, 2020 | Pubmed ID: 32422219 Is Low Alveolar Type II Cell in the Lungs of Elderly Linked to the Observed Severity of COVID-19? Antioxidants & Redox Signaling. 07, 2020 | Pubmed ID: 32323565 The Immune Response to Chronic Wound Infection in Immunocompetent Mice Advances in Wound Care. Feb, 2020 | Pubmed ID: 31903297 Proteomic Pathway Analysis of Monocyte-Derived Exosomes During Surgical Sepsis Identifies Immunoregulatory Functions Surgical Infections. Mar, 2020 | Pubmed ID: 31478785 Mitochondrial Connexin 43 in Sex-dependent Myocardial Responses and Estrogen-mediated Cardiac Protection Following Acute Ischemia/reperfusion Injury Basic Research in Cardiology. 11, 2019 | Pubmed ID: 31741053 Sociogenomic Approach to Wound Care: A New Patient-Centered Paradigm Advances in Wound Care. Nov, 2019 | Pubmed ID: 31637098 A Modified Collagen Dressing Induces Transition of Inflammatory to Reparative Phenotype of Wound Macrophages Scientific Reports. 10, 2019 | Pubmed ID: 31586077 Cutaneous Epithelial to Mesenchymal Transition Activator ZEB1 Regulates Wound Angiogenesis and Closure in a Glycemic Status-Dependent Manner Diabetes. 11, 2019 | Pubmed ID: 31439646 Disposable Patterned Electroceutical Dressing (PED-10) Is Safe for Treatment of Open Clinical Chronic Wounds Advances in Wound Care. Apr, 2019 | Pubmed ID: 31016066 Stabilized Collagen Matrix Dressing Improves Wound Macrophage Function and Epithelialization FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 02, 2019 | Pubmed ID: 30260708 Oral Tocotrienols Are Transported to Human Tissues and Delay the Progression of the Model for End-Stage Liver Disease Score in Patients The Journal of Nutrition. Feb, 2012 | Pubmed ID: 22298568 Commitment to Intellectual Honesty and Personal Responsibility Antioxidants & Redox Signaling. Apr, 2012 | Pubmed ID: 22239129 Propagation of Cutaneous Thermal Injury: A Mathematical Model Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Jan, 2012 | Pubmed ID: 22211391 Rebound Peer Review: a Viable Recourse for Aggrieved Authors? Antioxidants & Redox Signaling. Feb, 2012 | Pubmed ID: 22098370 MiRNA in Wound Inflammation and Angiogenesis Microcirculation (New York, N.Y. : 1994). Dec, 2011 | Pubmed ID: 22211762 MiR-210: the Master Hypoxamir Microcirculation (New York, N.Y. : 1994). Dec, 2011 | Pubmed ID: 22171547 Platelet-rich Fibrin Matrix Improves Wound Angiogenesis Via Inducing Endothelial Cell Proliferation Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Nov, 2011 | Pubmed ID: 22092846 Tocotrienols: the Lesser Known Form of Natural Vitamin E Indian Journal of Experimental Biology. Oct, 2011 | Pubmed ID: 22013739 Mitochondrially Targeted α-tocopheryl Succinate is Antiangiogenic: Potential Benefit Against Tumor Angiogenesis but Caution Against Wound Healing Antioxidants & Redox Signaling. Dec, 2011 | Pubmed ID: 21902599 Natural Vitamin E α-tocotrienol Protects Against Ischemic Stroke by Induction of Multidrug Resistance-associated Protein 1 Stroke; a Journal of Cerebral Circulation. Aug, 2011 | Pubmed ID: 21719775 Tocotrienol Vitamin E Protects Against Preclinical Canine Ischemic Stroke by Inducing Arteriogenesis Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Nov, 2011 | Pubmed ID: 21673716 Particulate β-glucan Induces TNF-α Production in Wound Macrophages Via a Redox-sensitive NF-κβ-dependent Pathway Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. May-Jun, 2011 | Pubmed ID: 21518092 MicroRNAs As New Maestro Conducting the Expanding Symphony Orchestra of Regenerative and Reparative Medicine Physiological Genomics. May, 2011 | Pubmed ID: 21467158 Differential Roles of Hypoxia Inducible Factor Subunits in Multipotential Stromal Cells Under Hypoxic Condition Journal of Cellular Biochemistry. Mar, 2011 | Pubmed ID: 21328454 MiRNA in Innate Immune Responses: Novel Players in Wound Inflammation Physiological Genomics. May, 2011 | Pubmed ID: 21139022 MiR-200b Targets Ets-1 and is Down-regulated by Hypoxia to Induce Angiogenic Response of Endothelial Cells The Journal of Biological Chemistry. Jan, 2011 | Pubmed ID: 21081489 MicroRNAs in Skin and Wound Healing Physiological Genomics. May, 2011 | Pubmed ID: 20959495 An Endovascular Canine Middle Cerebral Artery Occlusion Model for the Study of Leptomeningeal Collateral Recruitment Investigative Radiology. Jan, 2011 | Pubmed ID: 20856126 Prevalence of Obstructive Sleep Apnea in Patients with Chronic Wounds Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine. Dec, 2010 | Pubmed ID: 21206743 Detection of Macrophages Via Paramagnetic Vesicles Incorporating Oxidatively Tailored Cholesterol Ester: an Approach for Atherosclerosis Imaging Nanomedicine (London, England). Nov, 2010 | Pubmed ID: 21128718 Alpha-lipoic Acid Does Not Alter Stress Protein Response to Acute Exercise in Diabetic Brain Cell Biochemistry and Function. Dec, 2010 | Pubmed ID: 21104931 Differential Roles of Hypoxia Inducible Factor Subunits in Multipotential Stromal Cells Under Hypoxic Condition Journal of Cellular Biochemistry. Nov, 2010 | Pubmed ID: 21104912 Oxygenation State As a Driver of Myofibroblast Differentiation and Wound Contraction: Hypoxia Impairs Wound Closure The Journal of Investigative Dermatology. Dec, 2010 | Pubmed ID: 21068734 Reactive Oxygen Species Mediate Oxidized Low-density Lipoprotein-induced Inhibition of Oct-4 Expression and Endothelial Differentiation of Bone Marrow Stem Cells Antioxidants & Redox Signaling. Dec, 2010 | Pubmed ID: 20836655 Palm Oil-derived Natural Vitamin E Alpha-tocotrienol in Brain Health and Disease Journal of the American College of Nutrition. Jun, 2010 | Pubmed ID: 20823491 Endothelial Dysfunction in the Microcirculation of Patients with Obstructive Sleep Apnea American Journal of Respiratory and Critical Care Medicine. Dec, 2010 | Pubmed ID: 20656942 Acute Exercise and Thioredoxin-1 in Rat Brain, and Alpha-lipoic Acid and Thioredoxin-interacting Protein Response, in Diabetes International Journal of Sport Nutrition and Exercise Metabolism. Jun, 2010 | Pubmed ID: 20601738 Fra-2 Mediates Oxygen-sensitive Induction of Transforming Growth Factor Beta in Cardiac Fibroblasts Cardiovascular Research. Sep, 2010 | Pubmed ID: 20427335 Hypoxia Inducible MicroRNA 210 Attenuates Keratinocyte Proliferation and Impairs Closure in a Murine Model of Ischemic Wounds Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20308562 Macrophage Dysfunction Impairs Resolution of Inflammation in the Wounds of Diabetic Mice PloS One. 2010 | Pubmed ID: 20209061 Oxygen-sensitive Outcomes and Gene Expression in Acute Ischemic Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jul, 2010 | Pubmed ID: 20145654 Nanomolar Vitamin E Alpha-tocotrienol Inhibits Glutamate-induced Activation of Phospholipase A2 and Causes Neuroprotection Journal of Neurochemistry. Mar, 2010 | Pubmed ID: 20028458 Injectable, Rapid Gelling and Highly Flexible Hydrogel Composites As Growth Factor and Cell Carriers Acta Biomaterialia. Jun, 2010 | Pubmed ID: 20004745 Injectable, Highly Flexible, and Thermosensitive Hydrogels Capable of Delivering Superoxide Dismutase Biomacromolecules. Dec, 2009 | Pubmed ID: 19919046 Human Skin Wounds: a Major and Snowballing Threat to Public Health and the Economy Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Nov-Dec, 2009 | Pubmed ID: 19903300 A Mathematical Model of Ischemic Cutaneous Wounds Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009 | Pubmed ID: 19805373 Translational Informatics: Enabling High-throughput Research Paradigms Physiological Genomics. Nov, 2009 | Pubmed ID: 19737991 Fabrication and Characterization of Prosurvival Growth Factor Releasing, Anisotropic Scaffolds for Enhanced Mesenchymal Stem Cell Survival/growth and Orientation Biomacromolecules. Sep, 2009 | Pubmed ID: 19689108 Micromanaging Vascular Biology: Tiny MicroRNAs Play Big Band Journal of Vascular Research. 2009 | Pubmed ID: 19571573 Alpha-Lipoic Acid Modulates Thiol Antioxidant Defenses and Attenuates Exercise-induced Oxidative Stress in Standardbred Trotters Free Radical Research. Aug, 2009 | Pubmed ID: 19548154 Remodeling of the Ischemia-reperfused Murine Heart: 11.7-T Cardiac Magnetic Resonance Imaging of Contrast-enhanced Infarct Patches and Transmurality Antioxidants & Redox Signaling. Aug, 2009 | Pubmed ID: 19450139 Evidence-based Recommendations for the Use of Topical Oxygen Therapy in the Treatment of Lower Extremity Wounds The International Journal of Lower Extremity Wounds. Jun, 2009 | Pubmed ID: 19443899 Characterization of a Preclinical Model of Chronic Ischemic Wound Physiological Genomics. May, 2009 | Pubmed ID: 19293328 Inhibition of Vascular Smooth-muscle Cell Proliferation and Arterial Restenosis by HO-3867, a Novel Synthetic Curcuminoid, Through Up-regulation of PTEN Expression The Journal of Pharmacology and Experimental Therapeutics. Jun, 2009 | Pubmed ID: 19276401 Heat Shock Proteins in Diabetes and Wound Healing Current Protein & Peptide Science. Feb, 2009 | Pubmed ID: 19275675 Wound Healing Essentials: Let There Be Oxygen Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Jan-Feb, 2009 | Pubmed ID: 19152646 MicroRNA Expression in Response to Murine Myocardial Infarction: MiR-21 Regulates Fibroblast Metalloprotease-2 Via Phosphatase and Tensin Homologue Cardiovascular Research. Apr, 2009 | Pubmed ID: 19147652 Diabetes Impairs Exercise Training-associated Thioredoxin Response and Glutathione Status in Rat Brain Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2009 | Pubmed ID: 19074570 Gadolinium-containing Phosphatidylserine Liposomes for Molecular Imaging of Atherosclerosis Journal of Lipid Research. Nov, 2009 | Pubmed ID: 19017616 Oral Administration of Blueberry Inhibits Angiogenic Tumor Growth and Enhances Survival of Mice with Endothelial Cell Neoplasm Antioxidants & Redox Signaling. Jan, 2009 | Pubmed ID: 18817478 Neuroprotective and Antiinflammatory Properties of a Novel Demethylated Curcuminoid Antioxidants & Redox Signaling. Mar, 2009 | Pubmed ID: 18724833 Redox Modification of Ryanodine Receptors Contributes to Sarcoplasmic Reticulum Ca2+ Leak in Chronic Heart Failure Circulation Research. Dec, 2008 | Pubmed ID: 19008475 Minimally Invasive Neuroradiologic Model of Preclinical Transient Middle Cerebral Artery Occlusion in Canines Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008 | Pubmed ID: 18779582 Nutrigenomic Basis of Beneficial Effects of Chromium(III) on Obesity and Diabetes Molecular and Cellular Biochemistry. Oct, 2008 | Pubmed ID: 18636317 Differentiation of Bone Marrow Mesenchymal Stem Cells into the Smooth Muscle Lineage by Blocking ERK/MAPK Signaling Pathway Stem Cells and Development. Oct, 2008 | Pubmed ID: 18564029 Redox-active Antioxidant Modulation of Lipid Signaling in Vascular Endothelial Cells: Vitamin C Induces Activation of Phospholipase D Through Phospholipase A2, Lipoxygenase, and Cyclooxygenase Molecular and Cellular Biochemistry. Aug, 2008 | Pubmed ID: 18496733 Characterization of the Acute Temporal Changes in Excisional Murine Cutaneous Wound Inflammation by Screening of the Wound-edge Transcriptome Physiological Genomics. Jul, 2008 | Pubmed ID: 18460641 Topical Oxygen Therapy Induces Vascular Endothelial Growth Factor Expression and Improves Closure of Clinically Presented Chronic Wounds Clinical and Experimental Pharmacology & Physiology. Aug, 2008 | Pubmed ID: 18430064 Characterization of the Structural and Functional Changes in the Myocardium Following Focal Ischemia-reperfusion Injury American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2008 | Pubmed ID: 18375718 Wound Angiogenesis As a Function of Tissue Oxygen Tension: a Mathematical Model Proceedings of the National Academy of Sciences of the United States of America. Feb, 2008 | Pubmed ID: 18272493 HSP27 Regulates P53 Transcriptional Activity in Doxorubicin-treated Fibroblasts and Cardiac H9c2 Cells: P21 Upregulation and G2/M Phase Cell Cycle Arrest American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2008 | Pubmed ID: 18263706 Evidence for the Involvement of MiRNA in Redox Regulated Angiogenic Response of Human Microvascular Endothelial Cells Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2008 | Pubmed ID: 18258815 Redox Signals in Wound Healing Biochimica Et Biophysica Acta. Nov, 2008 | Pubmed ID: 18249195 Redox Regulation of the VEGF Signaling Path and Tissue Vascularization: Hydrogen Peroxide, the Common Link Between Physical Exercise and Cutaneous Wound Healing Free Radical Biology & Medicine. Jan, 2008 | Pubmed ID: 18191754 Assessment of Wound-site Redox Environment and the Significance of Rac2 in Cutaneous Healing Free Radical Biology & Medicine. Feb, 2008 | Pubmed ID: 18068132 Temperature Measurement on Tissue Surface During Laser Irradiation Medical & Biological Engineering & Computing. Feb, 2008 | Pubmed ID: 17891430 Leveraging an Information Warehouse to Create Translational Research Environment for Wound Care Center AMIA ... Annual Symposium Proceedings / AMIA Symposium. AMIA Symposium. 2007 | Pubmed ID: 18694039 Harnessing Hypoxic Adaptation to Prevent, Treat, and Repair Stroke Journal of Molecular Medicine (Berlin, Germany). Dec, 2007 | Pubmed ID: 18043901 12(S)-hydroperoxyeicosatetraenoic Acid (12-HETE) Increases Mitochondrial Nitric Oxide by Increasing Intramitochondrial Calcium Archives of Biochemistry and Biophysics. Dec, 2007 | Pubmed ID: 17963719 P21waf1/cip1/sdi1 As a Central Regulator of Inducible Smooth Muscle Actin Expression and Differentiation of Cardiac Fibroblasts to Myofibroblasts Molecular Biology of the Cell. Dec, 2007 | Pubmed ID: 17881730 Transcriptome-wide Analysis of Blood Vessels Laser Captured from Human Skin and Chronic Wound-edge Tissue Proceedings of the National Academy of Sciences of the United States of America. Sep, 2007 | Pubmed ID: 17728400 Transcriptome of Primary Adipocytes from Obese Women in Response to a Novel Hydroxycitric Acid-based Dietary Supplement DNA and Cell Biology. Sep, 2007 | Pubmed ID: 17708719 Tocotrienols: the Emerging Face of Natural Vitamin E Vitamins and Hormones. 2007 | Pubmed ID: 17628176 Regulation of C-Src Activity in Glutamate-induced Neurodegeneration The Journal of Biological Chemistry. Aug, 2007 | Pubmed ID: 17569670 Aerobically Derived Lactate Stimulates Revascularization and Tissue Repair Via Redox Mechanisms Antioxidants & Redox Signaling. Aug, 2007 | Pubmed ID: 17567242 Tocotrienols in Health and Disease: the Other Half of the Natural Vitamin E Family Molecular Aspects of Medicine. Oct-Dec, 2007 | Pubmed ID: 17507086 Algorithms for Mapping of MRNA Targets for MicroRNA DNA and Cell Biology. Apr, 2007 | Pubmed ID: 17465893 MicroRNA in Cutaneous Wound Healing: a New Paradigm DNA and Cell Biology. Apr, 2007 | Pubmed ID: 17465889 MiRNA: Licensed to Kill the Messenger DNA and Cell Biology. Apr, 2007 | Pubmed ID: 17465885 Alpha-lipoic Acid Modulates Heat Shock Factor-1 Expression in Streptozotocin-induced Diabetic Rat Kidney Antioxidants & Redox Signaling. Apr, 2007 | Pubmed ID: 17280490 Laser Microdissection and Capture of Pure Cardiomyocytes and Fibroblasts from Infarcted Heart Regions: Perceived Hyperoxia Induces P21 in Peri-infarct Myocytes American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2007 | Pubmed ID: 17158647 Mitochondrial Nitric Oxide Synthase Frontiers in Bioscience : a Journal and Virtual Library. 2007 | Pubmed ID: 17127362 The Role of the NADPH Oxidase Complex, P38 MAPK, and Akt in Regulating Human Monocyte/macrophage Survival American Journal of Respiratory Cell and Molecular Biology. Jan, 2007 | Pubmed ID: 16931806 DNA Microarray Technology in the Evaluation of Weight Management Potential of a Novel Calcium-potassium Salt of (-)-hydroxycitric Acid Toxicology Mechanisms and Methods. 2006 | Pubmed ID: 20021004 Natural Vitamin E Alpha-tocotrienol: Retention in Vital Organs in Response to Long-term Oral Supplementation and Withdrawal Free Radical Research. Jul, 2006 | Pubmed ID: 16984003 Transcriptome of the Subcutaneous Adipose Tissue in Response to Oral Supplementation of Type 2 Leprdb Obese Diabetic Mice with Niacin-bound Chromium Physiological Genomics. Nov, 2006 | Pubmed ID: 16940432 Characterization of the Potent Neuroprotective Properties of the Natural Vitamin E Alpha-tocotrienol Journal of Neurochemistry. Sep, 2006 | Pubmed ID: 16923160 Joint International Conference on EPR Spectroscopy and Wound Healing Antioxidants & Redox Signaling. Jul-Aug, 2006 | Pubmed ID: 16910786 Dietary Antioxidants for the Athlete Current Sports Medicine Reports. Jun, 2006 | Pubmed ID: 16822339 Heat Shock Protein 60 Response to Exercise in Diabetes: Effects of Alpha-lipoic Acid Supplementation Journal of Diabetes and Its Complications. Jul-Aug, 2006 | Pubmed ID: 16798478 Oxygen-sensitive Reset of Hypoxia-inducible Factor Transactivation Response: Prolyl Hydroxylases Tune the Biological Normoxic Set Point Free Radical Biology & Medicine. Jun, 2006 | Pubmed ID: 16785028 Postprandial Levels of the Natural Vitamin E Tocotrienol in Human Circulation Antioxidants & Redox Signaling. May-Jun, 2006 | Pubmed ID: 16771695 Regulation of Vascular Responses to Inflammation: Inducible Matrix Metalloproteinase-3 Expression in Human Microvascular Endothelial Cells is Sensitive to Antiinflammatory Boswellia Antioxidants & Redox Signaling. Mar-Apr, 2006 | Pubmed ID: 16677108 Transcriptome Analysis of the Ischemia-reperfused Remodeling Myocardium: Temporal Changes in Inflammation and Extracellular Matrix Physiological Genomics. May, 2006 | Pubmed ID: 16554547 Microarray Analysis of Gene Expression: Considerations in Data Mining and Statistical Treatment Physiological Genomics. May, 2006 | Pubmed ID: 16554544 Perceived Hyperoxia: Oxygen-induced Remodeling of the Reoxygenated Heart Cardiovascular Research. Jul, 2006 | Pubmed ID: 16483558 CDNA Microarray Screening in Food Safety Toxicology. Apr, 2006 | Pubmed ID: 16466843 Tocotrienols: Vitamin E Beyond Tocopherols Life Sciences. Mar, 2006 | Pubmed ID: 16458936 Laser Microdissection and Pressure-catapulting Technique to Study Gene Expression in the Reoxygenated Myocardium American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2006 | Pubmed ID: 16443670 Safety and Whole-body Antioxidant Potential of a Novel Anthocyanin-rich Formulation of Edible Berries Molecular and Cellular Biochemistry. Jan, 2006 | Pubmed ID: 16328973 Dermal Wound Healing is Subject to Redox Control Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2006 | Pubmed ID: 16126008 Wound Site Neutrophil Transcriptome in Response to Psychological Stress in Young Men Gene Expression. 2005 | Pubmed ID: 16358416 Delivery of Orally Supplemented Alpha-tocotrienol to Vital Organs of Rats and Tocopherol-transport Protein Deficient Mice Free Radical Biology & Medicine. Nov, 2005 | Pubmed ID: 16257640 Neuroprotective Properties of the Natural Vitamin E Alpha-tocotrienol Stroke; a Journal of Cerebral Circulation. Oct, 2005 | Pubmed ID: 16166580 Oxygen: from the Benefits of Inducing VEGF Expression to Managing the Risk of Hyperbaric Stress Antioxidants & Redox Signaling. Sep-Oct, 2005 | Pubmed ID: 16115043 Dermal Excisional Wound Healing in Pigs Following Treatment with Topically Applied Pure Oxygen Mutation Research. Nov, 2005 | Pubmed ID: 16105672 Access to Exercise and Its Relation to Cardiovascular Health and Gene Expression in Laboratory Animals Life Sciences. Sep, 2005 | Pubmed ID: 16002099 Relief from a Heavy Heart: Redox-sensitive NF-kappaB As a Therapeutic Target in Managing Cardiac Hypertrophy American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2005 | Pubmed ID: 15961373 Restraint Stress Alters Lung Gene Expression in an Experimental Influenza A Viral Infection Journal of Neuroimmunology. May, 2005 | Pubmed ID: 15833365 Human Genome Screen to Identify the Genetic Basis of the Anti-inflammatory Effects of Boswellia in Microvascular Endothelial Cells DNA and Cell Biology. Apr, 2005 | Pubmed ID: 15812241 Hyperbaric Oxygen Therapy Ameliorates Stress-impaired Dermal Wound Healing Brain, Behavior, and Immunity. May, 2005 | Pubmed ID: 15797310 Exercise-induced Oxidative Stress and Muscle Stress Protein Responses in Trotters European Journal of Applied Physiology. Jan, 2005 | Pubmed ID: 15221402 Tocotrienol: the Natural Vitamin E to Defend the Nervous System? Annals of the New York Academy of Sciences. Dec, 2004 | Pubmed ID: 15753140 Body Weight and Abdominal Fat Gene Expression Profile in Response to a Novel Hydroxycitric Acid-based Dietary Supplement Gene Expression. 2004 | Pubmed ID: 15200237 A Key Angiogenic Role of Monocyte Chemoattractant Protein-1 in Hemangioendothelioma Proliferation American Journal of Physiology. Cell Physiology. Oct, 2004 | Pubmed ID: 15163622 Exercise Training Modulates Heat Shock Protein Response in Diabetic Rats Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2004 | Pubmed ID: 15075301 DNA Microarray Technology in Nutraceutical and Food Safety Toxicology Letters. Apr, 2004 | Pubmed ID: 15068823 Protocols for Topical and Systemic Oxygen Treatments in Wound Healing Methods in Enzymology. 2004 | Pubmed ID: 15063699 Proximal Middle Cerebral Artery Occlusion Surgery for the Study of Ischemia-reoxygenation Injury in the Brain Methods in Enzymology. 2004 | Pubmed ID: 15063690 Proteomic Analysis of the Mammalian Cell Nucleus Methods in Enzymology. 2004 | Pubmed ID: 15063675 Survival Surgery for Coronary Occlusion and Reoxygenation in a Rodent Model Methods in Enzymology. 2004 | Pubmed ID: 15063673 Perceived Hyperoxia: Oxygen-regulated Signal Transduction Pathways in the Heart Methods in Enzymology. 2004 | Pubmed ID: 15063670 Reactive Oxygen Species and EGR-1 Gene Expression in Surgical Postoperative Peritoneal Adhesions World Journal of Surgery. Mar, 2004 | Pubmed ID: 14961185 Oxygen: at the Foundation of Wound Healing--introduction World Journal of Surgery. Mar, 2004 | Pubmed ID: 14961183 The General Case for Redox Control of Wound Repair Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Nov-Dec, 2003 | Pubmed ID: 14617282 Topical Oxygen As an Adjunct to Wound Healing: a Clinical Case Series Pathophysiology : the Official Journal of the International Society for Pathophysiology / ISP. Jan, 2003 | Pubmed ID: 14567939 Characterization of Perceived Hyperoxia in Isolated Primary Cardiac Fibroblasts and in the Reoxygenated Heart The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12952964 Significance of Oxygen Therapeutics Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Sep-Oct, 2003 | Pubmed ID: 12950645 Revisiting the Essential Role of Oxygen in Wound Healing American Journal of Surgery. Sep, 2003 | Pubmed ID: 12946829 Molecular Basis of Vitamin E Action: Tocotrienol Modulates 12-lipoxygenase, a Key Mediator of Glutamate-induced Neurodegeneration The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12917400 Redox Regulation of Mitochondrial Permeability Transition: Effects of Uncoupler, Lipoic Acid and Its Positively Charged Analog LA-plus and Selenium BioFactors (Oxford, England). 2003 | Pubmed ID: 12897451 Anti-angiogenic Property of Edible Berry in a Model of Hemangioma FEBS Letters. Jun, 2003 | Pubmed ID: 12782326 Molecular Mechanisms of Cardioprotection by a Novel Grape Seed Proanthocyanidin Extract Mutation Research. Feb-Mar, 2003 | Pubmed ID: 12628506 Oxygen Sensing by Primary Cardiac Fibroblasts: a Key Role of P21(Waf1/Cip1/Sdi1) Circulation Research. Feb, 2003 | Pubmed ID: 12595337 Presentation of Nitric Oxide Regulates Monocyte Survival Through Effects on Caspase-9 and Caspase-3 Activation The Journal of Biological Chemistry. Apr, 2003 | Pubmed ID: 12566444 Anti-angiogenic Property of Edible Berries Free Radical Research. Sep, 2002 | Pubmed ID: 12448828 Vitamin E Sensitive Genes in the Developing Rat Fetal Brain: a High-density Oligonucleotide Microarray Analysis FEBS Letters. Oct, 2002 | Pubmed ID: 12387859 Dermal Wound Healing Properties of Redox-active Grape Seed Proanthocyanidins Free Radical Biology & Medicine. Oct, 2002 | Pubmed ID: 12374620 Hemangioma Model for in Vivo Angiogenesis: Inducible Oxidative Stress and MCP-1 Expression in EOMA Cells Methods in Enzymology. 2002 | Pubmed ID: 12125369 Simultaneous Detection of Tocopherols and Tocotrienols in Biological Samples Using HPLC-coulometric Electrode Array Methods in Enzymology. 2002 | Pubmed ID: 12125359 Glutamate-induced C-Src Activation in Neuronal Cells Methods in Enzymology. 2002 | Pubmed ID: 12125347 Functional Genomics: High-density Oligonucleotide Arrays Methods in Enzymology. 2002 | Pubmed ID: 12078521 Cellular Protection with Proanthocyanidins Derived from Grape Seeds Annals of the New York Academy of Sciences. May, 2002 | Pubmed ID: 12074978 Oxygen, Oxidants, and Antioxidants in Wound Healing: an Emerging Paradigm Annals of the New York Academy of Sciences. May, 2002 | Pubmed ID: 12074976 Oxidant-induced Vascular Endothelial Growth Factor Expression in Human Keratinocytes and Cutaneous Wound Healing The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12068011 Flavonoids Differentially Regulate IFN Gamma-induced ICAM-1 Expression in Human Keratinocytes: Molecular Mechanisms of Action FEBS Letters. Jun, 2002 | Pubmed ID: 12044887 Copper-induced Vascular Endothelial Growth Factor Expression and Wound Healing American Journal of Physiology. Heart and Circulatory Physiology. May, 2002 | Pubmed ID: 11959648 Novel Bacterial Diversity and Fragmented EDNA Identified in Hyperbiofilm-Forming Pseudomonas Aeruginosa Rugose Small Colony Variant IScience. | Pubmed ID: 32058950 Electroceutical Treatment of Pseudomonas Aeruginosa Biofilms Scientific Reports. | Pubmed ID: 30765750 Staphylococcus Aureus Biofilm Infection Compromises Wound Healing by Causing Deficiencies in Granulation Tissue Collagen Annals of Surgery. | Pubmed ID: 30614873 Studying Host-Microbe Interactions in Wound Biofilm Formation (Video) | JoVE Mohamed El Masry1, Pramod Bhasme1, Shomita S. Mathew-Steiner1, Jessica Smith1, Thomas Smeenge1, Sashwati Roy1, Chandan K. Sen1 1Indiana Center for Regenerative Medicine & Engineering, Indiana University Health Comprehensive Wound Center, Department of Surgery, Indiana University School of Medicine JoVE 65301 Immunology and Infection A Small Animal Model of Ex Vivo Normothermic Liver Perfusion Eliza W. Beal1,2, Curtis Dumond1, Jung-Lye Kim1,2, Clifford Akateh1,2, Emre Eren1, Katelyn Maynard1, Chandan K. Sen3, Jay L. Zweier4, Kenneth Washburn2, Bryan A. Whitson1,3, Sylvester M. Black1,2 1Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center, Ohio State University Wexner Medical Center, 2Department of Surgery, Division of Transplant, Ohio State University Wexner Medical Center, 3Department of Surgery, Division of CardioThoracic Surgery, Ohio State University Wexner Medical Center, 4Department of Medicine, Ohio State University Wexner Medical Center JoVE 57541 Medicine Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function Ronald X. Xu1, Kun Huang2, Ruogu Qin1, Jiwei Huang1, Jeff S. Xu1, Liya Ding2, Urmila S. Gnyawali3, Gayle M. Gordillo3, Surya C. Gnyawali3,4, Chandan K. Sen3 1Department of Biomedical Engineering, The Ohio State University, 2Department of Biomedical Informatics, The Ohio State University, 3Comprehensive Wound Center, The Ohio State University, 4Department of Surgery, The Ohio State University JoVE 2095 Medicine High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart Surya C. Gnyawali1,2, Sashwati Roy1,2, Jason Driggs1,2, Savita Khanna1,2, Thomas Ryan2,3, Chandan K. Sen2 1Department of Surgery, The Ohio State University, 2Heart and Lung Research Institute, The Ohio State University, 3Department of Cardiovascular Medicine, The Ohio State University JoVE 1781 Medicine
Studying Host-Microbe Interactions in Wound Biofilm Formation (Video) | JoVE Mohamed El Masry1, Pramod Bhasme1, Shomita S. Mathew-Steiner1, Jessica Smith1, Thomas Smeenge1, Sashwati Roy1, Chandan K. Sen1 1Indiana Center for Regenerative Medicine & Engineering, Indiana University Health Comprehensive Wound Center, Department of Surgery, Indiana University School of Medicine JoVE 65301 Immunology and Infection
A Small Animal Model of Ex Vivo Normothermic Liver Perfusion Eliza W. Beal1,2, Curtis Dumond1, Jung-Lye Kim1,2, Clifford Akateh1,2, Emre Eren1, Katelyn Maynard1, Chandan K. Sen3, Jay L. Zweier4, Kenneth Washburn2, Bryan A. Whitson1,3, Sylvester M. Black1,2 1Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center, Ohio State University Wexner Medical Center, 2Department of Surgery, Division of Transplant, Ohio State University Wexner Medical Center, 3Department of Surgery, Division of CardioThoracic Surgery, Ohio State University Wexner Medical Center, 4Department of Medicine, Ohio State University Wexner Medical Center JoVE 57541 Medicine
Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function Ronald X. Xu1, Kun Huang2, Ruogu Qin1, Jiwei Huang1, Jeff S. Xu1, Liya Ding2, Urmila S. Gnyawali3, Gayle M. Gordillo3, Surya C. Gnyawali3,4, Chandan K. Sen3 1Department of Biomedical Engineering, The Ohio State University, 2Department of Biomedical Informatics, The Ohio State University, 3Comprehensive Wound Center, The Ohio State University, 4Department of Surgery, The Ohio State University JoVE 2095 Medicine
High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart Surya C. Gnyawali1,2, Sashwati Roy1,2, Jason Driggs1,2, Savita Khanna1,2, Thomas Ryan2,3, Chandan K. Sen2 1Department of Surgery, The Ohio State University, 2Heart and Lung Research Institute, The Ohio State University, 3Department of Cardiovascular Medicine, The Ohio State University JoVE 1781 Medicine
