Jeffrey C. Hansen Biochemistry and Molecular Biology Colorado State University Biography Publications Institution JoVE Articles Jeffrey C. Hansen has not added a biography. If you are Jeffrey C. Hansen and would like to personalize this page please email our Author Liaison for assistance. Publications The Role of the Nucleosome Acidic Patch in Modulating Higher Order Chromatin Structure Journal of the Royal Society, Interface / the Royal Society. May, 2013 | Pubmed ID: 23446052 Linker Histone H1.0 Interacts with an Extensive Network of Proteins Found in the Nucleolus Nucleic Acids Research. Feb, 2013 | Pubmed ID: 23435226 Human Mitotic Chromosome Structure: What Happened to the 30-nm Fibre? The EMBO Journal. Apr, 2012 | Pubmed ID: 22415369 Dynamic Fuzziness During Linker Histone Action Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22399316 Coil-to-helix Transitions in Intrinsically Disordered Methyl CpG Binding Protein 2 and Its Isolated Domains Protein Science : a Publication of the Protein Society. Apr, 2012 | Pubmed ID: 22294343 Activator-dependent Acetylation of Chromatin Model Systems Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22183601 Replacement of Histone H3 with CENP-A Directs Global Nucleosome Array Condensation and Loosening of Nucleosome Superhelical Termini Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21949362 The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays The Journal of Biological Chemistry. Jul, 2011 | Pubmed ID: 21532035 DNA Binding Restricts the Intrinsic Conformational Flexibility of Methyl CpG Binding Protein 2 (MeCP2) The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21467044 Nucleosome Distribution and Linker DNA: Connecting Nuclear Function to Dynamic Chromatin Structure Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Feb, 2011 | Pubmed ID: 21326360 Biophysical Analysis and Small-angle X-ray Scattering-derived Structures of MeCP2-nucleosome Complexes Nucleic Acids Research. May, 2011 | Pubmed ID: 21278419 Binding of the Rett Syndrome Protein, MeCP2, to Methylated and Unmethylated DNA and Chromatin IUBMB Life. Oct, 2010 | Pubmed ID: 21031501 Activator-dependent P300 Acetylation of Chromatin in Vitro: Enhancement of Transcription by Disruption of Repressive Nucleosome-nucleosome Interactions The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20720004 Histone Chaperones, Histone Acetylation, and the Fluidity of the Chromogenome Journal of Cellular Physiology. Aug, 2010 | Pubmed ID: 20432449 Unique Physical Properties and Interactions of the Domains of Methylated DNA Binding Protein 2 Biochemistry. May, 2010 | Pubmed ID: 20405910 Multifunctionality of the Linker Histones: an Emerging Role for Protein-protein Interactions Cell Research. May, 2010 | Pubmed ID: 20309017 Structural Characterization of H3K56Q Nucleosomes and Nucleosomal Arrays Biochimica Et Biophysica Acta. May-Jun, 2010 | Pubmed ID: 20100606 Human APOE Isoform-dependent Effects on Brain Beta-amyloid Levels in PDAPP Transgenic Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2009 | Pubmed ID: 19474305 Determinants of Histone H4 N-terminal Domain Function During Nucleosomal Array Oligomerization: Roles of Amino Acid Sequence, Domain Length, and Charge Density The Journal of Biological Chemistry. Jun, 2009 | Pubmed ID: 19395382 Recent Advances in MeCP2 Structure and Function Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Feb, 2009 | Pubmed ID: 19234536 Role of Nucleic Acid Binding in Sir3p-dependent Interactions with Chromatin Fibers Biochemistry. Jan, 2009 | Pubmed ID: 19099415 Chromatin Condensing Functions of the Linker Histone C-terminal Domain Are Mediated by Specific Amino Acid Composition and Intrinsic Protein Disorder Biochemistry. Jan, 2009 | Pubmed ID: 19072710 Chicken Erythrocyte Histone Octamer Preparation CSH Protocols. 2008 | Pubmed ID: 21356757 Malleable Machines Take Shape in Eukaryotic Transcriptional Regulation Nature Chemical Biology. Dec, 2008 | Pubmed ID: 19008886 The Effect of H3K79 Dimethylation and H4K20 Trimethylation on Nucleosome and Chromatin Structure Nature Structural & Molecular Biology. Oct, 2008 | Pubmed ID: 18794842 The Silent Information Regulator 3 Protein, SIR3p, Binds to Chromatin Fibers and Assembles a Hypercondensed Chromatin Architecture in the Presence of Salt Molecular and Cellular Biology. Jun, 2008 | Pubmed ID: 18362167 A Charged and Contoured Surface on the Nucleosome Regulates Chromatin Compaction Nature Structural & Molecular Biology. Nov, 2007 | Pubmed ID: 17965723 MeCP2-chromatin Interactions Include the Formation of Chromatosome-like Structures and Are Altered in Mutations Causing Rett Syndrome The Journal of Biological Chemistry. Sep, 2007 | Pubmed ID: 17660293 Novel Mechanism of Inhibition of Rat Kidney-type Glutaminase by Bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl Sulfide (BPTES) The Biochemical Journal. Sep, 2007 | Pubmed ID: 17581113 Intrinsic Disorder and Autonomous Domain Function in the Multifunctional Nuclear Protein, MeCP2 The Journal of Biological Chemistry. May, 2007 | Pubmed ID: 17371874 Nucleosome Recognition by the Piccolo NuA4 Histone Acetyltransferase Complex Biochemistry. Feb, 2007 | Pubmed ID: 17274630 The H3 Tail Domain Participates in Multiple Interactions During Folding and Self-association of Nucleosome Arrays Molecular and Cellular Biology. Mar, 2007 | Pubmed ID: 17242202 Multiple Modes of Interaction Between the Methylated DNA Binding Protein MeCP2 and Chromatin Molecular and Cellular Biology. Feb, 2007 | Pubmed ID: 17101771 Domain Organization and Quaternary Structure of the Saccharomyces Cerevisiae Silent Information Regulator 3 Protein, Sir3p Biochemistry. Dec, 2006 | Pubmed ID: 17176117 Linking Genome Structure and Function Through Specific Histone Acetylation ACS Chemical Biology. Mar, 2006 | Pubmed ID: 17163645 Developmental Biology: Holding Pattern for Histones Current Biology : CB. Nov, 2006 | Pubmed ID: 17084687 In Vitro Chromatin Self-association and Its Relevance to Genome Architecture Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2006 | Pubmed ID: 16936814 Chromatin Architectural Proteins Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 2006 | Pubmed ID: 16506095 Intrinsic Protein Disorder, Amino Acid Composition, and Histone Terminal Domains The Journal of Biological Chemistry. Jan, 2006 | Pubmed ID: 16301309 Salt-dependent Intra- and Internucleosomal Interactions of the H3 Tail Domain in a Model Oligonucleosomal Array The Journal of Biological Chemistry. Sep, 2005 | Pubmed ID: 16079127 The Core Histone N-terminal Tail Domains Function Independently and Additively During Salt-dependent Oligomerization of Nucleosomal Arrays The Journal of Biological Chemistry. Oct, 2005 | Pubmed ID: 16033758 The Histone H1 C-terminal Domain Binds to the Apoptotic Nuclease, DNA Fragmentation Factor (DFF40/CAD) and Stimulates DNA Cleavage Biochemistry. May, 2005 | Pubmed ID: 15910001 Nucleosome and Chromatin Fiber Dynamics Current Opinion in Structural Biology. Apr, 2005 | Pubmed ID: 15837178 Dissociation of Human Copper-zinc Superoxide Dismutase Dimers Using Chaotrope and Reductant. Insights into the Molecular Basis for Dimer Stability The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15485869 Biophysical Analysis of Specific Genomic Loci Assembled As Chromatin in Vivo Methods in Enzymology. 2004 | Pubmed ID: 14975296 Identification of Specific Functional Subdomains Within the Linker Histone H10 C-terminal Domain The Journal of Biological Chemistry. Mar, 2004 | Pubmed ID: 14668337 Revisiting the Structure and Functions of the Linker Histone C-terminal Tail Domain Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Jun, 2003 | Pubmed ID: 12897851 Formation of Higher-order Secondary and Tertiary Chromatin Structures by Genomic Mouse Mammary Tumor Virus Promoters Genes & Development. Jul, 2003 | Pubmed ID: 12842912 Chromatin Compaction by Human MeCP2. Assembly of Novel Secondary Chromatin Structures in the Absence of DNA Methylation The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12788925 Quantitative Characterization of Specific Genomic Promoters Using Agarose Gel Electrophoresis Biopolymers. Apr, 2003 | Pubmed ID: 12666180 Conformational Dynamics of the Chromatin Fiber in Solution: Determinants, Mechanisms, and Functions Annual Review of Biophysics and Biomolecular Structure. 2002 | Pubmed ID: 11988475 Phosphorylation of Linker Histones Regulates ATP-dependent Chromatin Remodeling Enzymes Nature Structural Biology. Apr, 2002 | Pubmed ID: 11887184 New Insights into Unwrapping DNA from the Nucleosome from a Single-molecule Optical Tweezers Method Proceedings of the National Academy of Sciences of the United States of America. Feb, 2002 | Pubmed ID: 11854477 The Essential Histone Variant H2A.Z Regulates the Equilibrium Between Different Chromatin Conformational States Nature Structural Biology. Mar, 2002 | Pubmed ID: 11850638 The SIN Domain of the Histone Octamer is Essential for Intramolecular Folding of Nucleosomal Arrays Nature Structural Biology. Mar, 2002 | Pubmed ID: 11836537 Assembly of Nucleosomal Arrays from Recombinant Core Histones and Nucleosome Positioning DNA Ryan A. Rogge1, Anna A. Kalashnikova1, Uma M. Muthurajan1, Mary E. Porter-Goff1, Karolin Luger1, Jeffrey C. Hansen1 1Biochemistry and Molecular Biology, Colorado State University JoVE 50354 Biology
Assembly of Nucleosomal Arrays from Recombinant Core Histones and Nucleosome Positioning DNA Ryan A. Rogge1, Anna A. Kalashnikova1, Uma M. Muthurajan1, Mary E. Porter-Goff1, Karolin Luger1, Jeffrey C. Hansen1 1Biochemistry and Molecular Biology, Colorado State University JoVE 50354 Biology