Karolin Luger

Publications

• Chaperone Nap1 Shields Histone Surfaces Used in a Nucleosome and Can Put H2A-H2B in an Unconventional Tetrameric Form
  Molecular Cell. Aug, 2013  |   Pubmed ID: 23973327
• Histone Chaperone FACT Action During Transcription Through Chromatin by RNA Polymerase II
  Proceedings of the National Academy of Sciences of the United States of America. May, 2013  |   Pubmed ID: 23610384
• Evidence for Monomeric Actin Function in INO80 Chromatin Remodeling
  Nature Structural & Molecular Biology. Apr, 2013  |   Pubmed ID: 23524535
• The Role of the Nucleosome Acidic Patch in Modulating Higher Order Chromatin Structure
  Journal of the Royal Society, Interface / the Royal Society. May, 2013  |   Pubmed ID: 23446052
• Linker Histone H1.0 Interacts with an Extensive Network of Proteins Found in the Nucleolus
  Nucleic Acids Research. Feb, 2013  |   Pubmed ID: 23435226
• Stability of Nucleosomes Containing Homogenously Ubiquitylated H2A and H2B Prepared Using Semisynthesis
  Journal of the American Chemical Society. Dec, 2012  |   Pubmed ID: 23163596
• Structure of Actin-related Protein 8 and Its Contribution to Nucleosome Binding
  Nucleic Acids Research. Nov, 2012  |   Pubmed ID: 22977180
• Yeast CAF-1 Assembles Histone (H3-H4)2 Tetramers Prior to DNA Deposition
  Nucleic Acids Research. Nov, 2012  |   Pubmed ID: 22941638
• Quantifying Chromatin-associated Interactions: the HI-FI System
  Methods in Enzymology. 2012  |   Pubmed ID: 22910210
• Alternative Modes of Binding of Poly(ADP-ribose) Polymerase 1 to Free DNA and Nucleosomes
  The Journal of Biological Chemistry. Sep, 2012  |   Pubmed ID: 22854955
• New Insights into Nucleosome and Chromatin Structure: an Ordered State or a Disordered Affair?
  Nature Reviews. Molecular Cell Biology. Jul, 2012  |   Pubmed ID: 22722606
• Proteins for Packaging, Partitioning, Processing, and Proofing of Nucleic Acids
  Current Opinion in Structural Biology. Feb, 2012  |   Pubmed ID: 22261637
• Fluorescence Strategies for High-throughput Quantification of Protein Interactions
  Nucleic Acids Research. Mar, 2012  |   Pubmed ID: 22121211
• Understanding Histone Acetyltransferase Rtt109 Structure and Function: How Many Chaperones Does It Take?
  Current Opinion in Structural Biology. Dec, 2011  |   Pubmed ID: 22023828
• Histone Chaperone FACT Coordinates Nucleosome Interaction Through Multiple Synergistic Binding Events
  The Journal of Biological Chemistry. Dec, 2011  |   Pubmed ID: 21969370
• Replacement of Histone H3 with CENP-A Directs Global Nucleosome Array Condensation and Loosening of Nucleosome Superhelical Termini
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011  |   Pubmed ID: 21949362
• Structure and Scm3-mediated Assembly of Budding Yeast Centromeric Nucleosomes
  Nature Communications. 2011  |   Pubmed ID: 21587230
• The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays
  The Journal of Biological Chemistry. Jul, 2011  |   Pubmed ID: 21532035
• The DEK Oncoprotein is a Su(var) That is Essential to Heterochromatin Integrity
  Genes & Development. Apr, 2011  |   Pubmed ID: 21460035
• The Histone Chaperone FACT: Structural Insights and Mechanisms for Nucleosome Reorganization
  The Journal of Biological Chemistry. May, 2011  |   Pubmed ID: 21454601
• Nucleosome Structure(s) and Stability: Variations on a Theme
  Annual Review of Biophysics. 2011  |   Pubmed ID: 21332355
• Biophysical Analysis and Small-angle X-ray Scattering-derived Structures of MeCP2-nucleosome Complexes
  Nucleic Acids Research. May, 2011  |   Pubmed ID: 21278419
• A Coupled Equilibrium Approach to Study Nucleosome Thermodynamics
  Methods in Enzymology. 2011  |   Pubmed ID: 21195232
• Nucleosome Accessibility Governed by the Dimer/tetramer Interface
  Nucleic Acids Research. Apr, 2011  |   Pubmed ID: 21177647
• The Transcription Factor Spn1 Regulates Gene Expression Via a Highly Conserved Novel Structural Motif
  Journal of Molecular Biology. Nov, 2010  |   Pubmed ID: 20875428
• Histone Chaperones, Histone Acetylation, and the Fluidity of the Chromogenome
  Journal of Cellular Physiology. Aug, 2010  |   Pubmed ID: 20432449
• The Histone Chaperone Nap1 Promotes Nucleosome Assembly by Eliminating Nonnucleosomal Histone DNA Interactions
  Molecular Cell. Mar, 2010  |   Pubmed ID: 20347425
• Rise of the Molecular Machines
  Current Opinion in Structural Biology. Feb, 2010  |   Pubmed ID: 20133121
• Structural Characterization of H3K56Q Nucleosomes and Nucleosomal Arrays
  Biochimica Et Biophysica Acta. May-Jun, 2010  |   Pubmed ID: 20100606
• Methods to Characterize the Effect of DNA-modifying Compounds on Nucleosomal DNA
  Methods in Molecular Biology (Clifton, N.J.). 2010  |   Pubmed ID: 19997884
• Structural and Biophysical Studies of Human PARP-1 in Complex with Damaged DNA
  Journal of Molecular Biology. Feb, 2010  |   Pubmed ID: 19962992
• A Positive Spin on the Centromere
  Cell. Jul, 2009  |   Pubmed ID: 19596232
• Nucleosome-binding Affinity As a Primary Determinant of the Nuclear Mobility of the Pioneer Transcription Factor FoxA
  Genes & Development. Apr, 2009  |   Pubmed ID: 19339686
• Histone Chaperone Specificity in Rtt109 Activation
  Nature Structural & Molecular Biology. Sep, 2008  |   Pubmed ID: 19172749
• The Effect of H3K79 Dimethylation and H4K20 Trimethylation on Nucleosome and Chromatin Structure
  Nature Structural & Molecular Biology. Oct, 2008  |   Pubmed ID: 18794842
• A Thermodynamic Model for Nap1-histone Interactions
  The Journal of Biological Chemistry. Nov, 2008  |   Pubmed ID: 18728017
• Histone Chaperones in Nucleosome Eviction and Histone Exchange
  Current Opinion in Structural Biology. Jun, 2008  |   Pubmed ID: 18534842
• A Beta-hairpin Comprising the Nuclear Localization Sequence Sustains the Self-associated States of Nucleosome Assembly Protein 1
  Journal of Molecular Biology. Jan, 2008  |   Pubmed ID: 18068721
• Structure of the Drosophila Nucleosome Core Particle Highlights Evolutionary Constraints on the H2A-H2B Histone Dimer
  Proteins. Apr, 2008  |   Pubmed ID: 17957772
• A Charged and Contoured Surface on the Nucleosome Regulates Chromatin Compaction
  Nature Structural & Molecular Biology. Nov, 2007  |   Pubmed ID: 17965723
• Effects of Photochemically Activated Alkylating Agents of the FR900482 Family on Chromatin
  Chemistry & Biology. May, 2007  |   Pubmed ID: 17524986
• Structure and Function of Nucleosome Assembly Proteins
  Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2006  |   Pubmed ID: 16936827
• Nucleosome Core Particles Containing a Poly(dA.dT) Sequence Element Exhibit a Locally Distorted DNA Structure
  Journal of Molecular Biology. Aug, 2006  |   Pubmed ID: 16860337
• A Feed-forward Repression Mechanism Anchors the Sin3/histone Deacetylase and N-CoR/SMRT Corepressors on Chromatin
  Molecular and Cellular Biology. Jul, 2006  |   Pubmed ID: 16809761
• The Histone Variant Macro-H2A Preferentially Forms "hybrid Nucleosomes"
  The Journal of Biological Chemistry. Sep, 2006  |   Pubmed ID: 16803903
• Kaposi's Sarcoma-associated Herpesvirus LANA Hitches a Ride on the Chromosome
  Cell Cycle (Georgetown, Tex.). May, 2006  |   Pubmed ID: 16721045
• Dynamic Nucleosomes
  Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 2006  |   Pubmed ID: 16506092
• The Nucleosomal Surface As a Docking Station for Kaposi's Sarcoma Herpesvirus LANA
  Science (New York, N.Y.). Feb, 2006  |   Pubmed ID: 16469929
• The Structure of Nucleosome Assembly Protein 1
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006  |   Pubmed ID: 16432217
• Structural Characterization of the Histone Variant MacroH2A
  Molecular and Cellular Biology. Sep, 2005  |   Pubmed ID: 16107708
• The Core Histone N-terminal Tail Domains Function Independently and Additively During Salt-dependent Oligomerization of Nucleosomal Arrays
  The Journal of Biological Chemistry. Oct, 2005  |   Pubmed ID: 16033758
• The Temperature of Flash-cooling Has Dramatic Effects on the Diffraction Quality of Nucleosome Crystals
  Acta Crystallographica. Section D, Biological Crystallography. Jul, 2005  |   Pubmed ID: 15983411
• Nucleosome and Chromatin Fiber Dynamics
  Current Opinion in Structural Biology. Apr, 2005  |   Pubmed ID: 15837178
• Structure and Dynamic Properties of Nucleosome Core Particles
  FEBS Letters. Feb, 2005  |   Pubmed ID: 15680970
• Nucleosomes in Solution Exist As a Mixture of Twist-defect States
  Journal of Molecular Biology. Jan, 2005  |   Pubmed ID: 15567414
• Nucleosome Assembly Protein 1 Exchanges Histone H2A-H2B Dimers and Assists Nucleosome Sliding
  The Journal of Biological Chemistry. Jan, 2005  |   Pubmed ID: 15516689
• H2A.Z Alters the Nucleosome Surface to Promote HP1alpha-mediated Chromatin Fiber Folding
  Molecular Cell. Nov, 2004  |   Pubmed ID: 15546624
• Defined Structural Changes Occur in a Nucleosome Upon Amt1 Transcription Factor Binding
  Journal of Molecular Biology. Oct, 2004  |   Pubmed ID: 15364568
• Structural Determinants for Generating Centromeric Chromatin
  Nature. Jul, 2004  |   Pubmed ID: 15282608
• Nucleosomes Containing the Histone Variant H2A.Bbd Organize Only 118 Base Pairs of DNA
  The EMBO Journal. Aug, 2004  |   Pubmed ID: 15257289
• Molecular Recognition of the Nucleosomal "supergroove"
  Proceedings of the National Academy of Sciences of the United States of America. May, 2004  |   Pubmed ID: 15100411
• A New Fluorescence Resonance Energy Transfer Approach Demonstrates That the Histone Variant H2AZ Stabilizes the Histone Octamer Within the Nucleosome
  The Journal of Biological Chemistry. Jun, 2004  |   Pubmed ID: 15020582
• Reconstitution of Nucleosome Core Particles from Recombinant Histones and DNA
  Methods in Enzymology. 2004  |   Pubmed ID: 14870657
• Crystal Structures of Histone Sin Mutant Nucleosomes Reveal Altered Protein-DNA Interactions
  The EMBO Journal. Jan, 2004  |   Pubmed ID: 14739929
• Preferential Binding of the Histone (H3-H4)2 Tetramer by NAP1 is Mediated by the Amino-terminal Histone Tails
  The Journal of Biological Chemistry. Nov, 2003  |   Pubmed ID: 12928440
• Tax Recruitment of CBP/p300, Via the KIX Domain, Reveals a Potent Requirement for Acetyltransferase Activity That is Chromatin Dependent and Histone Tail Independent
  Molecular and Cellular Biology. May, 2003  |   Pubmed ID: 12724399
• Structure and Dynamic Behavior of Nucleosomes
  Current Opinion in Genetics & Development. Apr, 2003  |   Pubmed ID: 12672489
• Structure and Dynamics of Nucleosomal DNA
  Biopolymers. Apr, 2003  |   Pubmed ID: 12666179
• Histone Chaperones and Nucleosome Assembly
  Current Opinion in Structural Biology. Feb, 2003  |   Pubmed ID: 12581654
• Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
  Journal of Molecular Biology. Feb, 2003  |   Pubmed ID: 12559907
• The Tail Does Not Always Wag the Dog
  Nature Genetics. Oct, 2002  |   Pubmed ID: 12244314
• Blocking Transcription Through a Nucleosome with Synthetic DNA Ligands
  Journal of Molecular Biology. Aug, 2002  |   Pubmed ID: 12144782
• Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 a Resolution
  Journal of Molecular Biology. Jun, 2002  |   Pubmed ID: 12079350
• The Essential Histone Variant H2A.Z Regulates the Equilibrium Between Different Chromatin Conformational States
  Nature Structural Biology. Mar, 2002  |   Pubmed ID: 11850638
• P300-mediated Tax Transactivation from Recombinant Chromatin: Histone Tail Deletion Mimics Coactivator Function
  Molecular and Cellular Biology. Jan, 2002  |   Pubmed ID: 11739728