Wei-Li Wu

Department of Physiology

National Cheng Kung University

Wei-Li Wu

Dr. Wei-Li Wu is an assistant professor in the Department of Physiology at the College of Medicine, National Cheng Kung University. Dr. Wu received his M.S. degree in marine biology with Dr. Hin-Kiu Mok and Dr. Chi-Ying Lee as advisors at National Sun Yat-sen University. Dr. Wu's master's study investigated neurotransmission during aggressive behavior using a fighting fish model. Then Dr. Wu received his Ph.D. degree in neuroscience with Dr. Chih-Cheng Chen as advisor at the Academia Sinica. In the Ph.D. training, he profiled the alternations of emotion-related behaviors in a mouse model with sensory deficits. After completing the doctoral degree, Dr. Wu joined the late Prof. Paul Patterson laboratory at Caltech as a postdoctoral scholar in neuroimmunology from 2012 to 2014. In Patterson laboratory, Dr. Wu focused on the gene x environment interactions in a preclinical mouse model of autism spectrum disorder (ASD) and schizophrenia, maternal immune activation. In 2014, Dr. Wu joined Prof. Sarkis Mazmanian laboratory at Caltech to carry on his works from the Patterson lab and to explore a brand-new direction: understanding how gut microbiota mediate mental homeostasis and disease. In Mazmanian laboratory, Dr. Wu interrogated the microbiota-based neural circuits underlying the social behavior using germ-free and antibiotics-treated mice, the mice deprived of the gut microbiota. In 2018, Dr. Wu set up his laboratory at National Cheng Kung University and continuously worked to unravel the neural mechanism by which gut microbiota impact brain circuits and host behaviors.

Publications