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Primäre orthotopische Glioma Xenografts rekapitulieren infiltratives Wachstum und Isocitrate Dehydrogenase I Mutation
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Primäre orthotopische Glioma Xenografts rekapitulieren infiltratives Wachstum und Isocitrate Dehydrogenase I Mutation

Article DOI: 10.3791/50865-v • 09:43 min • January 14th, 2014
January 14th, 2014 •
1, 1, 1, 1,2,3
1Department of Neurology, Vanderbilt University Medical Center, 2Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, 3Neurology Service, Veteran Affairs TVHS

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Maligne Gliome bilden eine heterogene Gruppe hochinfiltratischer gliaaler Neoplasmen mit ausgeprägten klinischen und molekularen Merkmalen. Primäre orthotopische Xenografts rekapitulieren die histopathologischen und molekularen Merkmale bösartiger Gliom-Subtypen in präklinischen Tiermodellen.

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Medizin Ausgabe 83 Gliom malignes Gliom primäres orthotopisches Xenograft Isocitrat-Dehydrogenase
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