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Glioma Xenoenxertos Ortotópicos Primários Recapitulam crescimento infiltrativo e isocitar mutação desidrogenase I
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Glioma Xenoenxertos Ortotópicos Primários Recapitulam crescimento infiltrativo e isocitar mutação desidrogenase I

Article DOI: 10.3791/50865-v • 09:43 min • January 14th, 2014
January 14th, 2014 •
1, 1, 1, 1,2,3
1Department of Neurology, Vanderbilt University Medical Center, 2Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, 3Neurology Service, Veteran Affairs TVHS

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Gliomas malignos constituem um grupo heterogêneo de neoplasias gliais altamente infiltrativas com características clínicas e moleculares distintas. Xenograftos ortotópicos primários recapitulam as características histopatológicas e moleculares de subtipos de glioma malignos em modelos animais pré-clínicos.

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Medicina Edição 83 Glioma glioma maligno xenoenxerto ortotópico primário isocitrícula desidrogenase
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