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JoVE Journal Cancer Research
Vier-kleur Fluorescentie Immunohistochemie van T-cel Subpopulations in Archival Formalin-Fixed, Paraffine-Embedded Human Oropharyngeal Squamous Cell Carcinoma Monsters
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Vier-kleur Fluorescentie Immunohistochemie van T-cel Subpopulations in Archival Formalin-Fixed, Paraffine-Embedded Human Oropharyngeal Squamous Cell Carcinoma Monsters

Article DOI: 10.3791/55589-v • 07:43 min • July 29th, 2017
July 29th, 2017 •
1, 2, 1,3
1Department of Pathology, Leiden University Medical Center, 2Department of Otorhinolaryngology and Head and Neck Surgery, Erasmus University Medical Center, 3Center for Gynecological Oncology Amsterdam, VU Medical Center

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Multiparameter fluorescentie immunohistochemie kan worden gebruikt om het aantal, relatieve verdeling en lokalisatie van immuuncellenpopulaties in de tumor micro-omgeving te beoordelen. Dit manuscript beschrijft het gebruik van deze techniek om T-cel subpopulaties in orofaryngeale kanker te analyseren.

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Cancer Research Immunologie hoofd- en nekkanker tumor micro-omgeving fluorescentiemicroscopie T-cel Th17-cel Treg IL-17
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